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2025

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The genetic prediction and classification of adult-onset type 1 diabetes using polygenic scores

Adult-onset type 1 diabetes (T1D) is a diagnostic challenge which can lead to misdiagnosis...

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Exploring long-term emotional and cognitive deficits in older adults with remote mild traumatic brain injury

Past research suggests there can be long-term consequences of a past concussion, such as...

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The relation between greenspace exposure and mental health

Exposure to greenspaces in urban areas has been linked to better mental health and...

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Understanding the characteristics of older adult volunteers sustainability

All community programs depend on volunteers, and anyone can be a volunteer. Seniors represent...

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Migraine and its relationship to cognitive function, hormonal factors, vascular disease and dementia in an aging population, an analysis of the prospective cohort longitudinal CLSA study

It is unclear whether individuals with migraine experience greater cognitive decline or higher dementia...

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Subjective and biological aging: Examining the association between perceived healthy aging and epigenetic age acceleration in a Canadian cohort

This study investigates the association between biological aging (as estimated by DNA methylation) and...

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Development of an equitable AI screening tool for ophthalmic and systemic diseases using retinal imaging and longitudinal cohort data

Vision loss and chronic systemic diseases are major public health concerns, particularly as the...

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The epigenetics of chronic liver disease

Steatotic liver disease (SLD), previously known as fatty liver disease, is the most common...

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Multi-organ functional ageing in the CLSA: Longitudinal phenotypes, omics, and mortality

We age in different ways. Some people lose strength or walking speed quickly; others...

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Multi-omics integrated analysis of obesity-related osteoarthritis

People who carry excess body weight have a much higher risk of developing osteoarthritis...

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Exploring the role of diet-induced premature immune aging on the development and prevention of early onset colorectal cancer

Colorectal cancer is the second leading cause of cancer-related death in Canada and is...

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Comparative evaluation of adiposity indices in predicting cardiometabolic multimorbidity: A prospective analysis from the Canadian Longitudinal Study on Aging

Obesity is a major risk factor for several chronic conditions, including diabetes, heart disease,...

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