Migraine and its relationship to cognitive function, hormonal factors, vascular disease and dementia in an aging population, an analysis of the prospective cohort longitudinal CLSA study It is unclear whether individuals with migraine experience greater cognitive decline or higher dementia... Learn More
Subjective and biological aging: Examining the association between perceived healthy aging and epigenetic age acceleration in a Canadian cohort This study investigates the association between biological aging (as estimated by DNA methylation) and... Learn More
Development of an equitable AI screening tool for ophthalmic and systemic diseases using retinal imaging and longitudinal cohort data Vision loss and chronic systemic diseases are major public health concerns, particularly as the... Learn More
The epigenetics of chronic liver disease Steatotic liver disease (SLD), previously known as fatty liver disease, is the most common... Learn More
Multi-organ functional ageing in the CLSA: Longitudinal phenotypes, omics, and mortality We age in different ways. Some people lose strength or walking speed quickly; others... Learn More
Multi-omics integrated analysis of obesity-related osteoarthritis People who carry excess body weight have a much higher risk of developing osteoarthritis... Learn More
Exploring the role of diet-induced premature immune aging on the development and prevention of early onset colorectal cancer Colorectal cancer is the second leading cause of cancer-related death in Canada and is... Learn More
Comparative evaluation of adiposity indices in predicting cardiometabolic multimorbidity: A prospective analysis from the Canadian Longitudinal Study on Aging Obesity is a major risk factor for several chronic conditions, including diabetes, heart disease,... Learn More
Associations between dietary patterns and menopausal health in middle-aged and older women: Findings from the CLSA: Study proposal As women age, they experience unique health challenges related to menopause, including increased risks... Learn More
Gender, social ties and diabetes in aging Canadians: A longitudinal study of diabetes-related depression and the mediation of nutrition factors Diabetes and depression are major health challenges affecting millions of Canadians, especially older adults.... Learn More
Examining how individual- and area-level factors affect trajectories of healthy aging: An analysis of respondents from the Canadian Longitudinal Study on Aging Healthy aging is a significant concern worldwide. Understanding the factors that affect it is... Learn More
The utility of heart rate fragmentation to predict cognitive decline in the Canadian Longitudinal Study on Aging The Alzheimer’s Society of Canada’s Landmark Study (2022) estimates that 1.7 million Canadians will... Learn More