Fu H. Obesity, plasma metabolites, and hypertension: A mediation Mendelian randomization study based on STROBE-MR guidelines. Medicine (Baltimore). 2025 Dec 19;104(51):e46709. doi: 10.1097/MD.0000000000046709. PMID: 41431085; PMCID: PMC12727316.
He X, Ma Y, Wu Q, Feng J, Wang W, Zhao S, Wang X. Causal pathways of plasma metabolites: unveiling metabolic associations in liver diseases. Nutr Metab (Lond). 2025 Nov 3;22(1):130. doi: 10.1186/s12986-025-01017-9. PMID: 41184928; PMCID: PMC12581490.
Huang C, Li Y, Li M, Ye X, Wang T, Liu N, Meng X, Gao Y, Wang X. Causal Effects of Plasma Metabolites on Leukemia: A Mendelian Randomization Study. Metabolites. 2025 Nov 3;15(11):719. doi: 10.3390/metabo15110719. PMID: 41295305; PMCID: PMC12654070.
Yu Y, Yang X, Deng J, Wu J, Yu R, Xiang Q. Longevity Code: Lipidome Associations and Mediated Metabolite Effects. Brain Behav. 2025 Nov;15(11):e70937. doi: 10.1002/brb3.70937. PMID: 41220160; PMCID: PMC12611319.
Chen H, Zhao H, Meng B, Liu Q. Novel causal associations between plasma metabolites and prostate cancer risk revealed by mendelian randomization. Metabol Open. 2025 Nov 14;28:100421. doi: 10.1016/j.metop.2025.100421. PMID: 41321402; PMCID: PMC12664657.
Liu Y, Tang R, Fang Y, Tian F, Gu T. Inflammatory cytokines mediate thoracic aortic aneurysm formation via plasma metabolites: A two-step Mendelian randomization and single cell sequencing-based investigation. Medicine (Baltimore). 2026 Feb 6;105(6):e47561. doi: 10.1097/MD.0000000000047561. PMID: 41650052; PMCID: PMC12885723.
Yan C, Wang B, Shi G, Ma W, Li K. Elucidating the causal relationships between cerebrospinal fluid metabolites and glioblastoma insights from mendelian randomization study. Neurosurg Rev. 2026 Feb 7;49(1):205. doi: 10.1007/s10143-025-04103-x. PMID: 41653332.
Yang W, Wang Y, Wang S, Zhai H, Che J, Wang X, Yang Y, Jia Z. The Association Between Irritable Bowel Syndrome and Generalized Anxiety Disorder and Influencing Factors: A Mediation Mendelian Randomization Study. Food Sci Nutr. 2026 Feb 10;14(2):e71525. doi: 10.1002/fsn3.71525. PMID: 41676012; PMCID: PMC12887448.
Zhang, Yin1,2,3,4,5; Yang, Wenlong1,2,3,4,5; A, Jixiang1,2,3,4,5; Wu, Chunyu1,2,3,4,5; Liu, Xiaoyan1,2,3,4,5; Qian, Juying1,2,3,4,5; Zhang, Shuning1,2,3,4,5,*. Gut microbiota in combination with blood metabolites and inflammatory cytokines reveals characteristics of hypertrophic cardiomyopathy: a Mendelian randomization study. Cardiology Plus ():10.1097/CP9.0000000000000126, September 03, 2025. | DOI: 10.1097/CP9.0000000000000126
Alaka SA, Ngan SC, MacPherson RE, Pickett W, Chen CP, Sze SK. Enhancing dementia risk prediction with heart rate and machine learning in the Canadian Longitudinal Study on Aging. J Alzheimers Dis. 2025 Oct 29:13872877251390562. doi: 10.1177/13872877251390562. Epub ahead of print. PMID: 41160465.
Li ZY, Li HL, Wang J, Shen QM, Zou YX, Yang DN, Tan YT, Xiang YB. Metabolomic insights into associations between adiposity markers and liver cancer risk: Results from a prospective cohort study and Mendelian randomization analysis. PLoS Med. 2026 Feb 2;23(2):e1004910. doi: 10.1371/journal.pmed.1004910. PMID: 41628182; PMCID: PMC12863527.
Henechowicz TL, Coleman PL, Gustavson DE, Mekki YN, Nayak S, Nitin R, Scartozzi AC, Tio ES, van Klei R, Felsky D, Thaut MH, Gordon RL. Polygenic Associations between Motor Behaviour, Neuromotor Traits, and Active Music Engagement in Four Cohorts. bioRxiv [Preprint]. 2025 Mar 30:2025.03.27.645667. doi: 10.1101/2025.03.27.645667. PMID: 40196524; PMCID: PMC11974849.