Impact of metformin use during pregnancy on fetal congenital malformations across 11 organ systems: a meta-analysis and drug-target Mendelian randomization study

Ji H, Wu Y, Wu S, Sun X, Yu Y, Hou L, Zhao R, Wang C, Yu Y, Ge Y, Wei Y, Luo Q, Wang L, Liu T, Zhang Z, Xiu J, Song Y, Li H, Gao S, Xue F, Chen H. Impact of metformin use during pregnancy on fetal congenital malformations across 11 organ systems: a meta-analysis and drug-target Mendelian randomization study. Diabetes Res Clin Pract. 2026 Jan 31;233:113118. doi: 10.1016/j.diabres.2026.113118. Epub ahead of print. PMID: 41628713.

Integrated Mendelian Randomization and Single‐Cell RNA Sequencing Analyses Reveal Lactate Metabolism as a Key Pathway in COVID‐19‐Induced Pulmonary Fibrosis

Zhang X, Jia L, Yeziya T, Yang S, Chen M, Mo Y, Tong X, Zhang L. Integrated Mendelian Randomization and Single-Cell RNA Sequencing Analyses Reveal Lactate Metabolism as a Key Pathway in COVID-19-Induced Pulmonary Fibrosis. Can Respir J. 2026 Jan 11;2026:1049336. doi: 10.1155/carj/1049336. PMID: 41532065; PMCID: PMC12791023.

Protective Causal Effects of CCL19, CCL23, and IL17A on Achilles Tendinitis: Insights from Bidirectional Mendelian Randomization and Metabolite-Mediated Pathway Analysis

Lu Wei, Wenqiang Wang, Xiang Chen, Shunan Dong, Hongjie Su, Puxiang Zhen, Xinyu Nie & Qikai Hua (2026) Protective Causal Effects of CCL19, CCL23, and IL17A on Achilles Tendinitis: Insights from Bidirectional Mendelian Randomization and Metabolite-Mediated Pathway Analysis, Orthopedic Research and Reviews, , 574286, DOI: 10.2147/ORR.S574286.