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2025

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Gender, Adverse Changes in Social Engagement and Risk of Unhealthy Eating: A Prospective Cohort Study of the Canadian Longitudinal Study on Aging (2011–2021)

Mehranfar S, Ceolin G, Madani Civi R, Keller H, Murphy RA, Cohen TR, Conklin AI. Gender, Adverse Changes in Social Engagement and Risk of Unhealthy Eating: A Prospective Cohort Study of the Canadian Longitudinal Study on Aging (2011–2021). Nutrients. 2025; 17(6):1005. https://doi.org/10.3390/nu17061005

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Elevated isoleucine may be a protective factor for primary hypertension: A pooled causal effect study

Shi Y, Liu H, Chen Y. Elevated isoleucine may be a protective factor for primary hypertension: A pooled causal effect study. Medicine (Baltimore). 2025 Feb 28;104(9):e41651. doi: 10.1097/MD.0000000000041651. PMID: 40020104; PMCID: PMC11875580.

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Blood metabolites reflect the effect of gut microbiota on differentiated thyroid cancer: a Mendelian randomization analysis

Zhang H, Li Y, Li L. Blood metabolites reflect the effect of gut microbiota on differentiated thyroid cancer: a Mendelian randomization analysis. BMC Cancer. 2025 Feb 28. 25. doi: 10.1186/s12885-025-13598-y

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The role of gut microbiota and plasma metabolites in ulcerative colitis: Insights from Mendelian randomization analysis

Zheng X, Fan J, Yin J, Chu Y. The role of gut microbiota and plasma metabolites in ulcerative colitis: Insights from Mendelian randomization analysis. Medicine (Baltimore). 2025 Feb 28;104(9):e41710. doi: 10.1097/MD.0000000000041710. PMID: 40020117; PMCID: PMC11875619.

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Mediating effect of X-26109 on the causal relationship between CD14+ CD16- monocyte activation complex and rheumatoid arthritis in Europe

Wang H, Chu J, Wang Y, Wu Y, Zhou W. Mediating effect of X-26109 on the causal relationship between CD14+ CD16- monocyte activation complex and rheumatoid arthritis in Europe. Clin Rheumatol. 2025 Mar;44(3):1095-1102. doi: 10.1007/s10067-025-07300-7. Epub 2025 Feb 7. PMID: 39915366.

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Causal Exposures in Pancreatic Cancer Incidence: Insights From Mendelian Randomization Studies

Mohamadkhani A, Ghanbari R, Shakeri R, Mohammadkhani MA, Pourshams A. Causal Exposures in Pancreatic Cancer Incidence: Insights From Mendelian Randomization Studies. JGH Open. 2025 Feb 3;9(2):e70105. doi: 10.1002/jgh3.70105. PMID: 39906083; PMCID: PMC11790352.

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Exploring Metabolomic Drivers of Colorectal and Gastric Cancer: A Mendelian Randomisation Study

Wang Y, Jian M, Hu J. Exploring Metabolomic Drivers of Colorectal and Gastric Cancer: A Mendelian Randomisation Study. J Coll Physicians Surg Pak. 2025 Feb;35(2):203-208. doi: 10.29271/jcpsp.2025.02.203. PMID: 39936199.

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Blunted cortisol as a biomarker of depression based on the attenuation hypothesis: A Mendelian randomization analysis using depression as exposure

Chan II. Blunted cortisol as a biomarker of depression based on the attenuation hypothesis: A Mendelian randomization analysis using depression as exposure. J Affect Disord. 2025 May 1;376:398-409. doi: 10.1016/j.jad.2025.02.016. Epub 2025 Feb 15. PMID: 39961449.

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Associations of cathepsins with pulmonary arterial hypertension mediated by circulating metabolites: A Mendelian randomization study

Yang S, Chen Q, Yang B. Associations of cathepsins with pulmonary arterial hypertension mediated by circulating metabolites: A Mendelian randomization study. Medicine (Baltimore). 2025 Jan 24;104(4):e41405. doi: 10.1097/MD.0000000000041405. PMID: 39854747; PMCID: PMC11771745.

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A Joint Bayesian Model for Change-Points and Heteroskedasticity Applied to the Canadian Longitudinal Study on Aging

Min J, Vishnyakova O, Brooks-Wilson A, Elliott LT. A Joint Bayesian Model for Change-Points and Heteroskedasticity Applied to the Canadian Longitudinal Study on Aging. J Comput Biol. 2025 Jan 20. doi: 10.1089/cmb.2024.0563. Epub ahead of print. PMID: 39829350.

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Peaceful dying among Canada’s elderly: An analysis of the Canadian Longitudinal Study on Aging

Aryal K, Jones A, Tanuseputro P, Griffith LE, Hebert PC, Kirkland S, Cook DJ, Costa AP. Peaceful dying among Canada’s elderly: An analysis of the Canadian Longitudinal Study on Aging. PLoS One. 2025 Jan 24;20(1):e0317014. doi: 10.1371/journal.pone.0317014. PMID: 39854434; PMCID: PMC11760003.

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Cardiac Conduction Delay for Sodium Channel Antagonist Antiseizure Medications An Analysis of the Canadian Longitudinal Study on Aging

Shlobin NA, Li J, Sander JW, Thijs RD. Cardiac Conduction Delay for Sodium Channel Antagonist Antiseizure Medications. Neurology. 2025 Feb 25;104(4). doi: 10.1212/WNL.0000000000210302

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