• English
  • Français
  • Update your details
Canadian Longitudinal Study on Aging (CLSA)
  • Participants
  • Trainees
  • Researchers
    • Data Access
    • Data Preview Portal
    • Data Availability
    • Magnolia
  • Resources
    • Participant Resources
    • Researcher Resources
    • Frequently Asked Questions
    • Approved Projects
    • Publications
    • CLSA Webinar Series
  • About
    • History
    • Impact
    • Team
    • Enabling Units
    • Funders & Partners
    • Governance
    • Opportunities
    • Videos
  • News
  • Contact

2025

Reset

Identification of factors associated with depression chronicity: An analysis of the Canadian Study on Aging (CLSA)

Spiegler G, Su Y, Li M, Meng X, Schmitz N. Identification of factors associated with depression chronicity: An analysis of the Canadian Study on Aging (CLSA). J Affect Disord. 2025 Aug 19;392:120079. doi: 10.1016/j.jad.2025.120079. Epub ahead of print. PMID: 40840723.

Learn More

RNFL Thickness in a Population-Based Cohort: The Canadian Longitudinal Study on Aging M2M (Machine-to-Machine) Study

Azizi A, da Costa DR, Scherer R, Malek DA, Samico GA, Medeiros FA. RNFL Thickness in a Population-Based Cohort: The Canadian Longitudinal Study on Aging M2M (Machine-to-Machine) Study. Am J Ophthalmol. 2025 Oct 4:S0002-9394(25)00530-6. doi: 10.1016/j.ajo.2025.09.051. Epub ahead of print. PMID: 41052566.

Learn More

Retinal Vessel Traits and Age-Related Eye Disease in the Canadian Longitudinal Study on Aging

O’Neil A, Welikala RA, Barman S, Owen CG, Rudnicka AR, Rakesh M, Roy-Gagnon MH, Maberley D, Freeman EE. Retinal Vessel Traits and Age-Related Eye Disease in the Canadian Longitudinal Study on Aging. Clin Exp Ophthalmol. 2025 Jun 14. doi: 10.1111/ceo.14566. Epub ahead of print. PMID: 40515626.

Learn More

The association between primary ovarian insufficiency and increased multimorbidity in a large prospective cohort (Canadian Longitudinal Study on Aging)

Kirubarajan A, Sohel N, Mayhew A, Griffith LE, Raina P, Shea AK. The association between primary ovarian insufficiency and increased multimorbidity in a large prospective cohort (Canadian Longitudinal Study on Aging). Fertil Steril. 2025 Feb;123(2):289-299. doi: 10.1016/j.fertnstert.2024.08.345. Epub 2024 Aug 29. PMID: 39216544.

Learn More

Causal associations between 1400 circulating metabolites and spontaneous abortion: A bidirectional 2-sample Mendelian randomization study

Zhou X, Fang YX, Zhang DW, Ma LY, Yao MM. Causal associations between 1400 circulating metabolites and spontaneous abortion: A bidirectional 2-sample Mendelian randomization study. Medicine (Baltimore). 2025 Nov 21;104(47):e45981. doi: 10.1097/MD.0000000000045981. PMID: 41305730; PMCID: PMC12643647.

Learn More

Role of metabolites in mediating the effect of gut microbiota on Crohn disease: A two-step Mendelian randomization (MR) study

Shi H, Peng Q. Role of metabolites in mediating the effect of gut microbiota on Crohn disease: A two-step Mendelian randomization (MR) study. Medicine (Baltimore). 2025 Nov 28;104(48):e46253. doi: 10.1097/MD.0000000000046253. PMID: 41327678; PMCID: PMC12662486.

Learn More

1400 plasma metabolites and Sjögren’s syndrome: a Mendelian randomization analysis

Cui Q, Zhou B, Feng Y, Huang Q. 1400 plasma metabolites and Sjögren’s syndrome: a Mendelian randomization analysis. Clin Rheumatol. 2025 Dec 3. doi: 10.1007/s10067-025-07799-w. Epub ahead of print. PMID: 41335288.

Learn More

Causal association of circulating metabolites with female infertility: a bidirectional mendelian randomization analysis

Liu L, Liu B, Liao M, Zeng B, Qin L, Li M. Causal association of circulating metabolites with female infertility: a bidirectional mendelian randomization analysis. Metabolomics. 2025 Oct 16;21(6):149. doi: 10.1007/s11306-025-02357-6. PMID: 41102584.

Learn More

Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis

Khan A, Yen FS, Unlu G, DelGaudio NL, Erdal R, Xiao M, Wangdu K, Cho K, Gamazon ER, Patti GJ, Birsoy K. Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis. Cell Metab. 2025 Oct 10:S1550-4131(25)00434-6. doi: 10.1016/j.cmet.2025.09.015. Epub ahead of print. PMID: 41075780.

Learn More

Gut Microbiotas, Plasma Metabolites, and Autism Spectrum Disorder: A Bidirectional Mendelian Randomization Analysis

Zhou J, Fu Z, Gao Y, An C, Zhang Z, Zhong X, Tian L, Yang X, Zhang J, Zhang Q, Wang D, Li N. Gut Microbiotas, Plasma Metabolites, and Autism Spectrum Disorder: A Bidirectional Mendelian Randomization Analysis. Pathogens. 2025 Nov 10;14(11):1137. doi: 10.3390/pathogens14111137. PMID: 41305374; PMCID: PMC12655273.

Learn More

Blood metabolites mediate gut microbiota effects on depression: A Mendelian randomization study

Zhang YW, Zhao SS, Li XY, Liu HZ. Blood metabolites mediate gut microbiota effects on depression: A Mendelian randomization study. J Affect Disord. 2025 Nov 4;394(Pt B):120478. doi: 10.1016/j.jad.2025.120478. Epub ahead of print. PMID: 41197911.

Learn More

Bidirectional Causal Associations Between Plasma Metabolites and Parkinson’s Disease

Zhao M, Li T, Shen H, Baranova A, Chandhoke V, Zhang F. Bidirectional Causal Associations Between Plasma Metabolites and Parkinson’s Disease. Mol Neurobiol. 2025 Nov 12;63(1):30. doi: 10.1007/s12035-025-05306-5. PMID: 41222837.

Learn More

Previous

1234…13
Next

Subscribe to our newsletter

* indicates required
Canadian Longitudinal Study on Aging (CLSA)

info@clsa-elcv.ca

1 (866) 999-8303

Researchers
  • Data Access
  • Data Preview Portal
  • Data Availability
  • Brain Health Studies
  • COVID-19 Studies
Participants
  • Update Your Details
  • Privacy, Confidentiality & Ethics
  • Newsletters
Resources
  • Approved Projects
  • Publications
  • Webinars
  • Frequently Asked Questions
About CLSA
  • History
  • Impact
  • News & Webinars
  • Team
  • Enabling Units
  • Funders & Partners
  • Governance
  • Opportunities
  • Videos

© 2026 Canadian Longitudinal Study on Aging (CLSA). All rights reserved.

  • Privacy Policy
  • Terms and Conditions

Crafted with by Forge and Smith.