Join us Thursday, April 23 at 12 PM ET for the CLSA webinar “Metabolomic sweet spot clock predicts mortality and age-related diseases in the Canadian Longitudinal Study on Aging.” The webinar will be presented by Dr. Olga Vishnyakova, postdoctoral fellow at the BC Cancer Research Institute and the Department of Biomedical Physiology and Kinesiology at Simon Fraser University.
Chronological age does not capture individual health or resilience. People of the same chronological age may exhibit diverse aging phenotypes shaped by environmental exposures, lifestyle, psychological conditions, and genetic factors. There is growing interest in developing biomarkers of biological aging that better reflect heterogeneity in aging trajectories and the processes underlying healthy aging.
This webinar presents a study that developed an interpretable metabolomic biomarker of biological aging using CLSA data. The approach identifies metabolites related to health, estimates their optimal levels, and models deviations from these “sweet spots” to construct a metabolomic clock linked to health status. The webinar will highlight how this framework can be used to study aging heterogeneity, resilience, and risk of health decline, and how metabolomic data may help advance more informative measures of healthy aging.
Dr. Olga Vishnyakova is a Postdoctoral Fellow at the BC Cancer Research Institute and the Department of Biomedical Physiology and Kinesiology at Simon Fraser University. She holds BSc and MSc degrees in Applied Mathematics, an MSc in Computing Science from Radboud University, and a PhD in Computational Biology from Simon Fraser University. Dr. Vishnyakova’s research focuses on healthy aging, using multi-omic approaches to study heterogeneity in aging and the biological mechanisms underlying resilience.
