Multi-organ functional ageing in the CLSA: Longitudinal phenotypes, omics, and mortality We age in different ways. Some people lose strength or walking speed quickly; others... Learn More
Multi-omics integrated analysis of obesity-related osteoarthritis People who carry excess body weight have a much higher risk of developing osteoarthritis... Learn More
Using multi-omics to predict chronic diseases outcomes As people age, the risk od developing chronic diseases increases, including sarcopenia, cancer, obesity,... Learn More
Multi-omics kidney aging trajectories across environments Premature aging involves harmful changes in the body over time, increasing disease risk. The... Learn More
Diet and 6-year muscle and cognitive function trajectories in the Canadian Longitudinal Study on Aging: combining traditional and omics approaches While heart health studies recommend eating more plant-based proteins, healthy aging studies highlight the... Learn More
Multi-omics determinants underlying dementia susceptibility Our research aims to protect people’s brains from dementia, a condition that causes memory... Learn More
Investigating the associations between ambient air pollution exposure and genomics, epigenomics and metabolomics Cancer and other age-related diseases are known to be associated with high air pollution... Learn More
Investigation of the aging process – a multi-omics approach The rate of aging varies from individual to individual due to several factors, including... Learn More
Degenerative protein modifications (DPMs) as molecular mediators connecting socio-demographic profile to the onset of age-related diseases We have identified a set of degenerative protein modifications (DPMs) in patients’ tissues, resulting... Learn More
Identification of genetic variants associated with frailty – a genome-wide association study The world population is getting older, and we are observing the same phenomenon in... Learn More
Interactive visualization of genetic variant-trait associations in the CLSA dataset The CLSA study collected data on thousands of traits and hundreds of millions of... Learn More
Identifying novel genetic factors predisposing to inherited cardiac disorders Inherited cardiac disorders arise from genetic variations and can manifest as cardiomyopathies or arrhythmic... Learn More
