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Approved Projects

CLSA approved projects encompass a broad spectrum of research topics and questions aimed at comprehensively understanding the aging process and its impact on health and well-being.

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A causal inference approach to life satisfaction and outcome-wide health

The biopsychosocial model of health emphasizes the importance of patients’ well-being in determining their...

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Adverse childhood experiences, genomic influences, and acceleration of biological aging in middle-aged and older adults in the CLSA

Adverse childhood experiences (ACEs), including childhood exposure to abuse, neglect, and intimate partner violence...

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Influenza, pneumococcal, shingles, and COVID-19 vaccinations among immigrant and non-immigrant older adults in Canada

Older adults are recommended to receive the influenza, pneumococcal, shingles, and COVID-19 vaccines, as...

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Interactive visualization of genetic variant-trait associations in the CLSA dataset

The CLSA study collected data on thousands of traits and hundreds of millions of...

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Reference values and the psychometric properties of the Life-Space Assessment in the Canadian Longitudinal Study on Aging

The Life-Space Assessment (LSA) is a questionnaire that measures everyday mobility. It assesses the...

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CLSA COVID-19 Brain Study – neuropsychological cohort and neuroimaging cohort

Our overarching goal is to better understand the consequences of the COVID-19 pandemic on...

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Factors associated with increased chronic pain risk among Canadian veterans: Insights from Life After Service Study and Canadian Longitudinal Study on Aging

Chronic pain, which lasts for more than three months, is a significant health concern...

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Predicting clinical manifestations of Parkinson’s Disease using polygenic risk scores

People living with Parkinson’s disease experience a variety of symptoms including problems with movement,...

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Understanding the social determinants of healthy ageing – a multinational longitudinal cohort comparison study

Social determinants of health (SDH) refer to the social, economic, and environmental conditions in...

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Hypothetical interventions for real world impact: addressing the obesity epidemic in older adults

The Canadian population is aging rapidly and older adults represent the fastest growing part...

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Identifying novel genetic factors predisposing to inherited cardiac disorders

Inherited cardiac disorders arise from genetic variations and can manifest as cardiomyopathies or arrhythmic...

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Mental and physical health associations in large biological datasets: using developmental neuroscience to inform risk and resilience to chronic disease

Early life environment exposure is the foundation of a healthy life-course trajectory. Exposure to...

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