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Canadian Longitudinal Study on Aging (CLSA)
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The role of cognitive reserve in cognitive decline associated with retirement

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Parkinson’s disease risk and phenoconversion: a polygenic risk score approach

Parkinson’s disease (PD) is a common neurodegenerative disease in older adults. Health conditions like...

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Investigating the associations between ambient air pollution exposure and genomics, epigenomics and metabolomics

Cancer and other age-related diseases are known to be associated with high air pollution...

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Genetic analyses of healthy aging: buffering and exploratory analyses

Genetic variants are like spelling differences in genes. Genetic buffering is when a variant...

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Studying vascular predictors for the onset of stroke and dementia in older adults

In Canada, about one-third of seniors have at least 2 of the 10 most...

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Examining multimorbidity, social and physical functioning and health care utilization in Canada

In Canada the majority of older adults live with more than one chronic condition....

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Facilitating interpretation of cognitive impairment: the development of reliable changes scores for the cognitive measures in the Canadian Longitudinal Study on Aging

The CLSA collects information about the cognitive functioning of English- and French-speaking participants aged...

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A longitudinal investigation on the impacts of the urban built environment (greenness, noise and walkability) on depression, anxiety, and positive mental health of CLSA participants

Features of urban natural and built environments (green spaces and walkable and quiet neighborhoods)...

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Causes and consequences of social isolation and loneliness among marginalized older adults

Social isolation and loneliness among older adults are associated with worse health, and older...

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Longitudinal insights: exploring employment experiences and well-being among Canadian immigrants over time

Canada has the highest proportion of immigrants among G8 countries. With immigration being a...

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Degenerative protein modifications (DPMs) as molecular mediators connecting socio-demographic profile to the onset of age-related diseases

We have identified a set of degenerative protein modifications (DPMs) in patients’ tissues, resulting...

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Identify underlying pathways and characterize key moderators of the higher life satisfaction and lower mortality risk association

In light of our nation’s 1) rapidly ageing population, 2) rising medical costs, and...

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Canadian Longitudinal Study on Aging (CLSA)

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