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epigenetics

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Using multi-omics to predict chronic diseases outcomes

As people age, the risk od developing chronic diseases increases, including sarcopenia, cancer, obesity,...

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Diet and 6-year muscle and cognitive function trajectories in the Canadian Longitudinal Study on Aging: combining traditional and omics approaches

While heart health studies recommend eating more plant-based proteins, healthy aging studies highlight the...

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Epigenetic aging and social adversity as synergistic predictors of oral health in older Canadians living with multimorbidity: a machine learning approach

Oral health is an essential determinant of overall quality of life. As individuals age,...

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How does socioeconomic position become biologically embedded? a cross-national comparison of associations between socioeconomic position and epigenetic aging in middle-aged older adults in Canada and the US

People with lower socioeconomic position (SEP) tend to have poorer health than those with...

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Adverse childhood experiences, genomic influences, and acceleration of biological aging in middle-aged and older adults in the CLSA

Adverse childhood experiences (ACEs), including childhood exposure to abuse, neglect, and intimate partner violence...

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A comprehensive approach to quantifying chronic inflammation in older adults

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Measuring healthy aging through epigenetics

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Development of epigenetic age prediction algorithm

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Association between mitochondrial DNA copy number and nuclear DNA methylation in cardiovascular disease and aging

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Psychosocial stress and epigenetic aging as common pathways to oral disease and multimorbidity

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Sex differences in accelerated epigenetic age and cognitive decline: possible role of biological, social, and lifestyle factors

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Adverse childhood experiences, genomic influences, and acceleration of biological aging in middle-aged and older adults in the Canadian Longitudinal Study on Aging (CLSA)

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