Inflammation

Villaplana-Velasco A, Perrot N, Hang Y, Chong M, Trucco E, Mookiah MRK, Nelson W, Petch J, Gerstein HC, Raina P, Yusuf S, Bernabeu MO, Tenesa A, Rawlik K, Pare G, Doney A, Pairo-Castineira E, Pigeyre M. Mendelian randomization study implicates inflammaging biomarkers in retinal vasculature, cardiovascular diseases, and longevity. Sci Adv. 2025 Oct 24;11(43):eadu1985. doi: 10.1126/sciadv.adu1985. Epub 2025 Oct 24. PMID: 41134885; PMCID: PMC12551708.

Yaskolka Meir A, Yun H, Hu J, Li J, Liu J, Bever A, Ratanatharathorn A, Song M, Eliassen AH, Chibnik L, Koenen K, Pare G, Stampfer MJ, Liang L. Cross-omics risk scores of inflammation markers are associated with all-cause mortality: The Canadian Longitudinal Study on Aging. Am J Hum Genet. 2025 Aug 7;112(8):1892-1905. doi: 10.1016/j.ajhg.2025.06.009. Epub 2025 Jul 8. PMID: 40633542; PMCID: PMC12338089.

Verschoor CP, Vlasschaert C, Rauh MJ, Paré G. A DNA methylation based measure outperforms circulating CRP as a marker of chronic inflammation and partly reflects the monocytic response to long-term inflammatory exposure: A Canadian Longitudinal Study on Aging analysis. Aging Cell. 2023 Jul;22(7):e13863. doi: 10.1111/acel.13863. Epub 2023 May 4. PMID: 37139638.

Thompson C, Legault J, Moullec G, Martineau-Dussault MÈ, Baltzan M, Cross N, Dang-Vu TT, Gervais N, Einstein G, Hanly P, Ayas N, Lorrain D, Kaminska M, Gagnon JF, Lim A, Carrier J, Gosselin N. Association between risk of obstructive sleep apnea, inflammation and cognition after 45 years old in the Canadian Longitudinal Study on Aging. Sleep Med. 2022 Mar;91:21-30. doi: 10.1016/j.sleep.2022.02.006. Epub 2022 Feb 16. PMID: 35245788.