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GWAS Summary Data

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Causal relationship between plasma metabolites and hypertension: A Mendelian randomization study

Yang F, Wu Y, Zhu H, Ye X, Tang L. Causal relationship between plasma metabolites and hypertension: A Mendelian randomization study. Medicine (Baltimore). 2025 Oct 3;104(40):e45077. doi: 10.1097/MD.0000000000045077. PMID: 41054079; PMCID: PMC12499832.

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Unveiling causal links between serum amino acid levels and risk of hepatobiliary neoplasms by Mendelian randomization study

Zhai A, Ren L, Zhong Y, Zou R, Yang S, Jin Y, Hu H, Li F. Unveiling causal links between serum amino acid levels and risk of hepatobiliary neoplasms by Mendelian randomization study. Medicine (Baltimore). 2025 Oct 24;104(43):e45491. doi: 10.1097/MD.0000000000045491. PMID: 41137215; PMCID: PMC12558176.

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A genome-wide association study identified 10 novel genomic loci associated with intrinsic capacity

Beyene MB, Visvanathan R, Alemu R, Benyamin B, Bhattacharjee R, Beyene HB, Theou O, Cesari M, Beard JR, Amare AT. A genome-wide association study identified 10 novel genomic loci associated with intrinsic capacity. J Gerontol A Biol Sci Med Sci. 2025 Oct 5;80(11):glaf196. doi: 10.1093/gerona/glaf196. PMID: 41066301; PMCID: PMC12510315.

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Causal relationships between plasma metabolites and prostate cancer: A Mendelian randomization study exploring immune and inflammatory mediators

Huang M, Ning D, Tong T, Teng Q, Cao F, Guan Y, Wang Y, Lei H, Pang J. Causal relationships between plasma metabolites and prostate cancer: A Mendelian randomization study exploring immune and inflammatory mediators. Current Urology. 2025 Sep 11. DOI: 10.1097/CU9.0000000000000307

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The role of gut microbiota and plasma metabolites in osteoporosis: Insights from Mendelian randomization analysis

Zhu W, Ma S, Zheng X, Yin J. The role of gut microbiota and plasma metabolites in osteoporosis: Insights from Mendelian randomization analysis. Medicine (Baltimore). 2025 Sep 12;104(37):e44409. doi: 10.1097/MD.0000000000044409. PMID: 40958276; PMCID: PMC12440530.

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The Role of Plasma Metabolites in Mediating the Effect of Gut Microbiota on Obstructive Sleep Apnea: A Two-Step, Two-Sample Mendelian Randomization Study

Wang X, Zhao R, Guo J, Yang K, Xu B. The Role of Plasma Metabolites in Mediating the Effect of Gut Microbiota on Obstructive Sleep Apnea: A Two-Step, Two-Sample Mendelian Randomization Study. Nat Sci Sleep. 2025 Sep 3;17:2119-2130. doi: 10.2147/NSS.S527778. PMID: 40927699; PMCID: PMC12415091.

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Unlocking the Secrets: Causal Associations Between Blood Metabolites and Aspergillosis

Ma Y, Du W. Unlocking the Secrets: Causal Associations Between Blood Metabolites and Aspergillosis. Curr Microbiol. 2025 Sep 4;82(10):490. doi: 10.1007/s00284-025-04465-x. PMID: 40906222.

Mendelian randomisation analysis to discover plasma metabolites mediating the effect of obesity on cancer risk

Yates T, Went M, Mills C, Law P, Gockel I, Maj C, Schumacher J, Palles C, Houlston R. Mendelian randomisation analysis to discover plasma metabolites mediating the effect of obesity on cancer risk. Br J Cancer. 2025 Nov;133(9):1344-1353. doi: 10.1038/s41416-025-03170-7. Epub 2025 Sep 2. PMID: 40897820; PMCID: PMC12572173.

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Investigating Causal Links between Metabolite Profiles and Ulcerative Colitis: A Bidirectional Mendelian Randomization Study

Zarei P, Kamali Z, Keshteli AH, Sedeh PA, Vaez A. Investigating Causal Links between Metabolite Profiles and Ulcerative Colitis: A Bidirectional Mendelian Randomization Study. J Med Signals Sens. 2025 Sep 1;15:27. doi: 10.4103/jmss.jmss_16_25. PMID: 40949582; PMCID: PMC12431707.

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Plasma metabolites mediate the effects of circulating immune cell phenotypes on prostate cancer: A 2-step Mendelian randomization study

Zhou W, Ding J, Shen Y, Huang F, Xu D. Plasma metabolites mediate the effects of circulating immune cell phenotypes on prostate cancer: A 2-step Mendelian randomization study. Medicine (Baltimore). 2025 Sep 5;104(36):e44282. doi: 10.1097/MD.0000000000044282. PMID: 40922267; PMCID: PMC12419313.

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Multi-omics integration reveals CYTL1 and H6PD as key regulators of tumor metabolism in mesothelioma

Ma J, Zhang H, Yu L, Guo Y, Ming J, Guo Z. Multi-omics integration reveals CYTL1 and H6PD as key regulators of tumor metabolism in mesothelioma. Genes Genomics. 2025 Oct;47(10):1049-1063. doi: 10.1007/s13258-025-01667-2. Epub 2025 Aug 25. PMID: 40853611.

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Dissecting Causal Relationships Between Gut Microbiota, Plasma Metabolites and Bladder Cancer: A Two-Step Mendelian Randomization Study

Che K, Qian D, Cui S, Xie F. Dissecting Causal Relationships Between Gut Microbiota, Plasma Metabolites and Bladder Cancer: A Two-Step Mendelian Randomization Study. Health Sci Rep. 2025 Sep 9;8(9):e71206. doi: 10.1002/hsr2.71206. PMID: 40937009; PMCID: PMC12420358.

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