Publications
Kolifarhood G, Parisien M, Fillingim M, Chen C, Chen Y, Dimitrov N, Zidan M, Hanumunthadu L, Her PH, Bhatnagar S, Diatchenko L, Grant AV. Causal evidence linking chronic pain genetics to late-onset asthma via the nervous system. Br J Anaesth. 2026 Jan 17:S0007-0912(25)00823-2. doi: 10.1016/j.bja.2025.11.020. Epub ahead of print. PMID: 41547614.
Zhang X, Jia L, Yeziya T, Yang S, Chen M, Mo Y, Tong X, Zhang L. Integrated Mendelian Randomization and Single-Cell RNA Sequencing Analyses Reveal Lactate Metabolism as a Key Pathway in COVID-19-Induced Pulmonary Fibrosis. Can Respir J. 2026 Jan 11;2026:1049336. doi: 10.1155/carj/1049336. PMID: 41532065; PMCID: PMC12791023.
Lu Wei, Wenqiang Wang, Xiang Chen, Shunan Dong, Hongjie Su, Puxiang Zhen, Xinyu Nie & Qikai Hua (2026) Protective Causal Effects of CCL19, CCL23, and IL17A on Achilles Tendinitis: Insights from Bidirectional Mendelian Randomization and Metabolite-Mediated Pathway Analysis, Orthopedic Research and Reviews, , 574286, DOI: 10.2147/ORR.S574286.
Chen H, Wang F, Guo Y, Zhu Y, Li X, Meng Z, Feng X, Yang Y, Wu S, Li S, Li B. Association of plasma metabolites with epigenetic age acceleration: a two-sample Mendelian randomization study. Biogerontology. 2025 Dec 20;27(1):25. doi: 10.1007/s10522-025-10372-2. PMID: 41420675.
Fu H. Obesity, plasma metabolites, and hypertension: A mediation Mendelian randomization study based on STROBE-MR guidelines. Medicine (Baltimore). 2025 Dec 19;104(51):e46709. doi: 10.1097/MD.0000000000046709. PMID: 41431085; PMCID: PMC12727316.
He X, Ma Y, Wu Q, Feng J, Wang W, Zhao S, Wang X. Causal pathways of plasma metabolites: unveiling metabolic associations in liver diseases. Nutr Metab (Lond). 2025 Nov 3;22(1):130. doi: 10.1186/s12986-025-01017-9. PMID: 41184928; PMCID: PMC12581490.
Huang C, Li Y, Li M, Ye X, Wang T, Liu N, Meng X, Gao Y, Wang X. Causal Effects of Plasma Metabolites on Leukemia: A Mendelian Randomization Study. Metabolites. 2025 Nov 3;15(11):719. doi: 10.3390/metabo15110719. PMID: 41295305; PMCID: PMC12654070.
Yu Y, Yang X, Deng J, Wu J, Yu R, Xiang Q. Longevity Code: Lipidome Associations and Mediated Metabolite Effects. Brain Behav. 2025 Nov;15(11):e70937. doi: 10.1002/brb3.70937. PMID: 41220160; PMCID: PMC12611319.
Chen H, Zhao H, Meng B, Liu Q. Novel causal associations between plasma metabolites and prostate cancer risk revealed by mendelian randomization. Metabol Open. 2025 Nov 14;28:100421. doi: 10.1016/j.metop.2025.100421. PMID: 41321402; PMCID: PMC12664657.
Liu Y, Tang R, Fang Y, Tian F, Gu T. Inflammatory cytokines mediate thoracic aortic aneurysm formation via plasma metabolites: A two-step Mendelian randomization and single cell sequencing-based investigation. Medicine (Baltimore). 2026 Feb 6;105(6):e47561. doi: 10.1097/MD.0000000000047561. PMID: 41650052; PMCID: PMC12885723.
Yan C, Wang B, Shi G, Ma W, Li K. Elucidating the causal relationships between cerebrospinal fluid metabolites and glioblastoma insights from mendelian randomization study. Neurosurg Rev. 2026 Feb 7;49(1):205. doi: 10.1007/s10143-025-04103-x. PMID: 41653332.
Yang W, Wang Y, Wang S, Zhai H, Che J, Wang X, Yang Y, Jia Z. The Association Between Irritable Bowel Syndrome and Generalized Anxiety Disorder and Influencing Factors: A Mediation Mendelian Randomization Study. Food Sci Nutr. 2026 Feb 10;14(2):e71525. doi: 10.1002/fsn3.71525. PMID: 41676012; PMCID: PMC12887448.