Genetics

Han X, Steven K, Qassim A, Marshall HN, Bean C, Tremeer M, An J, Siggs OM, Gharahkhani P, Craig JE, Hewitt AW, Trzaskowski M, MacGregor S. Automated AI labeling of optic nerve head enables insights into cross-ancestry glaucoma risk and genetic discovery in >280,000 images from UKB and CLSA. Am J Hum Genet. 2021 Jul 1;108(7):1204-1216. doi: 10.1016/j.ajhg.2021.05.005. Epub 2021 Jun 1. PMID: 34077762; PMCID: PMC8322932.

Cai J, Zhang J, Fu Y, Zhu M, Zhu C, Ji C, Jin C, Ma H, Zhu M, Zhang C, Wu L, Du L, Ma H. Integrative genomic and metabolomic analyses identify novel associations between mQTLs and common diseases in Han Chinese. J Biomed Res. 2026 May 25:1-16. doi: 10.7555/JBR.39.20250530. Epub ahead of print. PMID: 42135028.

Liu Y, Chen X, Liu Y, Lu Y, Zhu Y, Chen L, Li J. The Causal Association between Plasma Metabolites-Mediated Immune Cells and Myocardial Infarction: A Mendelian Randomization Study. Arq Bras Cardiol. 2026 May 29;123(4):e20260026. Portuguese, English. doi: 10.36660/abc.20250026. PMID: 42233835; PMCID: PMC13155783.

Ding K, Jiang W, Lei M, Gao Y. Dissecting Immune Mechanisms Underlying Sarcopenia Using Multi-omics Approaches. Calcif Tissue Int. 2026 May 2;117(1):74. doi: 10.1007/s00223-026-01524-8. PMID: 42068367.

Hao W, Song R, Lv H, Song C. Integrative Multi-Omics Analysis Unveils Biomarkers Linking the Gut Microbiota, Blood Metabolites, and Recurrent Pregnancy Loss. Int J Womens Health. 2026 Apr 30;18:598767. doi: 10.2147/IJWH.S598767. PMID: 42087990; PMCID: PMC13138343.

Ding L, Cao W, Zhou Z, Mei Z, Chen B, Lu X, Chen W. Exploring the causal effect of genetically predicted blood and cerebrospinal fluid metabolites and metabolic pathways on intracranial aneurysm. J Int Med Res. 2026 Apr;54(4):3000605261442755. doi: 10.1177/03000605261442755. Epub 2026 Apr 28. PMID: 42050911; PMCID: PMC13145066.

Liang Q, Zeng T. Disentangling causal relationships linking the oral microbiome, metabolism, inflammation, and dental caries via Mendelian randomization. Medicine (Baltimore). 2026 Apr 24;105(17):e48263. doi: 10.1097/MD.0000000000048263. PMID: 42071828; PMCID: PMC13124402.

Gao P, Ye D, Li Q, Bai L, Xu X, Fang X. Association between blood metabolites and chronic respiratory diseases: A Mendelian randomization study. Medicine (Baltimore). 2026 Apr 24;105(17):e48317. doi: 10.1097/MD.0000000000048317. PMID: 42071799; PMCID: PMC13124415.

Li S, Zhang M, Wang X, Huang Y, Huang B, Wang M, Liu M, Cui J. Genetic Association Between Sex Hormones, Serum Urate, and Gout: A Comprehensive Mendelian Randomization Study. Int J Endocrinol. 2026 Apr 20;2026:8839727. doi: 10.1155/ije/8839727. PMID: 42016019; PMCID: PMC13092932.

Wang H, Ghajari H, Jayasinghe GJMSR, Seviiri M, Gordon SD, Neale RE, Pandeya N, Olsen CM, MacGregor S, Whiteman DC, Law MH. Genetics vs clinical risk scores for melanoma prediction. Br J Dermatol. 2026 Apr 10:ljag126. doi: 10.1093/bjd/ljag126. Epub ahead of print. PMID: 41968088.

Rivera-Herrera AL, Rouleau M, Singbo MNU, Cuppens T, Carmichael PH, Droit A, Simonyan D, Laurin D, Guillemette C. Exploring the association between common genetic deletions and aging: insights from the Canadian Longitudinal Study on Aging. Geroscience. 2026 Jun 24. doi: 10.1007/s11357-026-02363-z. Epub ahead of print. PMID: 42340576.

Ingold N, Seviiri M, Ong JS, Gordon S, Neale RE, Whiteman DC, Olsen CM, MacGregor S, Law MH. Genetic Analysis of Perceived Youthfulness Reveals Differences in How Men’s and Women’s Age Is Assessed. J Invest Dermatol. 2024 Mar 7:S0022-202X(24)00180-5. doi: 10.1016/j.jid.2024.02.019. Epub ahead of print. PMID: 38460809.