Publications
Borhan S, An Nguyen LM, Pigeyre M, Pare G, Adachi J, Papaioannou A, Griffith LE, Thabane L, Raina P. Ordinal GWAS analysis of the frailty phenotype identified a novel locus at 12q22 that underscores the role of the neurological and immune systems. NPJ Aging. 2026 Apr 22;12(1):55. doi: 10.1038/s41514-026-00363-z. PMID: 42020437; PMCID: PMC13103308.
Yao Y, Yang X, Yan J, Lv H, Yue Z, Yu J, Lin X, Qian C, Zhang H, Liu Z, Ye M. Causal Relationship of Polyunsaturated Fatty Acids With Mental Disorders: A Systematic Review and Meta-analysis. Nutr Rev. 2026 May 8:nuaf225. doi: 10.1093/nutrit/nuaf225. Epub ahead of print. PMID: 42100925.
Mutailipu M, Aini A, Mutailifu D, Maimaitirexiti S, Maiwulanjiang M, Paerhati D, Maimaitiaili A. miR-221-3p-mediated CPT2 suppression links cardiomyocyte metabolic stress to NET-associated inflammation in myocardial ischemia-reperfusion injury: Multi-omics evidence and experimental validation. Int Immunopharmacol. 2026 Aug 10;187:117265. doi: 10.1016/j.intimp.2026.117265. Epub ahead of print. PMID: 42574811.
Yin Wang, Yuqian Luo. Genetically predicted plasma metabolites link the pathway from gut microbiome to Hashimoto’s thyroiditis. In Silico Research in Biomedicine, Volume 2. 2026. 100483. ISSN 3050-7871. doi:10.1016/j.insi.2026.100483.
Liu C, Wang J, Yuan Y, Long P, Xiao G, Wang C. Genetically predicted N-acetylisoleucine levels mediate the association between PB/PC% lymphocyte and normal pressure hydrocephalus: A mediation Mendelian randomization study. Medicine (Baltimore). 2026 Jun 19;105(25):e49395. doi: 10.1097/MD.0000000000049395. PMID: 42332499; PMCID: PMC13286318.
Yu C, Dong L, Zhang R, Li H, Shi X, Wu H, Zhou W, Li Y, Wei WB. Causal Effects of Gut Microbiota and Associated Metabolites on Retinal Diseases and Visual Impairment: A Mendelian Randomization Study. J Ophthalmol. 2026 Jun 17;2026:4233490. doi: 10.1155/joph/4233490. PMID: 42318308; PMCID: PMC13273394.
Cao YN, Wang L, Fan HS, Zhang ZJ. Chronic Obstructive Pulmonary Disease Influence on Lung Cancer Risk Through Blood Metabolite Mediation: A Two-Sample Mendelian Randomisation and Mediation Analysis. Int J Chron Obstruct Pulmon Dis. 2026 Jun 20;21:608125. doi: 10.2147/COPD.S608125. PMID: 42367346; PMCID: PMC13295007.
Chen Y, Wang W, Xu X, Huang X, Wei B, Jin H, Pan Q, Yang Y, Wang Z, Feng C, Chen L, Zhao Z, Su Y. Causal effects among hypertension, osteoporosis, and metabolites: A Mendelian randomization study. J Chin Med Assoc. 2026 Jul 1;89(7):544-553. doi: 10.1097/JCMA.0000000000001397. Epub 2026 Jun 16. PMID: 42299496; PMCID: PMC13387780.
Ryu J, Lee C. Bayesian colocalization of psychiatric disorder GWAS signals with molecular quantitative trait loci highlights histone involvement and neuroimmune dysregulation in pathogenesis. Psychiatry Res. 2026 Oct;364:117287. doi: 10.1016/j.psychres.2026.117287. Epub 2026 Jun 15. PMID: 42320287.
Yang H, Liu Y, Zhu T, Xiao Z, Wang H, Zhu S, Chen Y. Gut Microbiome-Metabolite Interactions Contribute to Esophageal Cancer Risk: Evidence From Mendelian Randomization and Multiomics Integration. Int J Genomics. 2026 Jun 8;2026:5967802. doi: 10.1155/ijog/5967802. PMID: 42266611; PMCID: PMC13243870.
Zhou K, Zhang Q, Liu M, Yan Y, Wang J. Causal relationship between inflammatory proteins and attention deficit hyperactivity disorder: A serum-metabolites-mediated Mendelian randomization analysis. Medicine (Baltimore). 2026 May 29;105(22):e48963. doi: 10.1097/MD.0000000000048963. PMID: 42216364; PMCID: PMC13225583.
Wang Q, Xie Y, Wu X, Jin S, Zhen W, Yu S, Sun Y, Sun W, Xu J, Zhang H. Toothache and Alzheimer’s Disease: A Mendelian Randomization Study of the NAAG-CD33 Neuroimmune Axis. J Pain Res. 2026 May 26;19:603587. doi: 10.2147/JPR.S603587. PMID: 42222647; PMCID: PMC13222017.