Publications
Pasquet R, Xu M, Sylvestre MP, Keezer MR. Comparison of three frailty measures for predicting hospitalization and mortality in the Canadian Longitudinal Study on Aging. Aging Clin Exp Res. 2024 Feb 29;36(1):48. doi: 10.1007/s40520-024-02706-w. PMID: 38418612; PMCID: PMC10902012.
Halliwell C, Moyer R, O’Brien MW. Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging. Arthritis Care Res (Hoboken). 2026 Aug 17. doi: 10.1002/acr.80139. Epub ahead of print. PMID: 42605908.
Borhan S, An Nguyen LM, Pigeyre M, Pare G, Adachi J, Papaioannou A, Griffith LE, Thabane L, Raina P. Ordinal GWAS analysis of the frailty phenotype identified a novel locus at 12q22 that underscores the role of the neurological and immune systems. NPJ Aging. 2026 Apr 22;12(1):55. doi: 10.1038/s41514-026-00363-z. PMID: 42020437; PMCID: PMC13103308.
Shivgulam ME, Halliwell C, Theou O, O’Brien MW. Longitudinal associations between movement and sarcopenia, gait speed, and grip strength differ by frailty level in the Canadian Longitudinal Study on Aging. Arch Gerontol Geriatr. 2026 Jul 17;150:106363. doi: 10.1016/j.archger.2026.106363. Epub ahead of print. PMID: 42537596.
Halliwell C, Moyer R, Legge A, Theou O, Bélanger M, Mekari S, O’Brien MW. Frailty is associated with lower-limb osteoarthritis incidence over six-years regardless of sex and type of frailty index in the Canadian longitudinal study on aging. Osteoarthr Cartil Open. 2026 May 27;8(3):100827. doi: 10.1016/j.ocarto.2026.100827. PMID: 42283064; PMCID: PMC13251491.
Mehrabi F, Phillips NA, Pichora-Fuller MK, Wittich W, Andrew MK, Mick P. Frailty Progression Moderates the Association Between Sensory and Cognitive Trajectories Over 6 Years: Evidence From the Canadian Longitudinal Study on Aging. Ear Hear. 2026 Jun 1. doi: 10.1097/AUD.0000000000001839. Epub ahead of print. PMID: 42223330.
Courish MK, O’Brien MW, Shivgulam ME, MacDonald EE, Mekari S, Theou O. The Impact of a Prior Traumatic Brain Injury and Injury Characteristics on Frailty in the Canadian Longitudinal Study on Aging. Arch Phys Med Rehabil. 2026 Jun;107(6):1322-1329. doi: 10.1016/j.apmr.2026.01.021. Epub 2026 Jan 29. PMID: 41620060.
Rafiq T, Ma J, Joshi D, Mayhew A, Griffith L, van den Heuvel E, Raina P. Dietary metabolomic determinants of frailty through inflammation in the Canadian Longitudinal Study on Aging. NPJ Aging. 2026 Mar 23. doi: 10.1038/s41514-026-00367-9. Epub ahead of print. PMID: 41872230.
Courish MK, O’Brien MW, Shivgulam ME, MacDonald EE, Mekari S, Theou O. The Impact of a Prior Traumatic Brain Injury & Injury Characteristics on Frailty in the Canadian Longitudinal Study on Aging. Arch Phys Med Rehabil. 2026 Jan 29:S0003-9993(26)00044-4. doi: 10.1016/j.apmr.2026.01.021. Epub ahead of print. PMID: 41620060.
Griffith LE, Terrera GM, van den Heuvel E, Khattar J, Hogan DB, O’Connell M, Levasseur M, Raina P. Physical, Psychological, Cognitive and Social Frailty Domains in Community-Dwelling Adults Aged 45-85: a Cross-sectional Analysis of the Canadian Longitudinal Study on Aging (CLSA). Can Geriatr J. 2025 Dec 3;28(4):343-352. doi: 10.5770/cgj.28.872. PMID: 41306637; PMCID: PMC12646700.
Duignan L, Dutton D. Comprehensiveness vs Efficiency: A Cross-Sectional Analysis of the Association Between Allostatic Load and the Frailty Index Using the CLSA. J Am Med Dir Assoc. 2025 Sep 8;26(11):105829. doi: 10.1016/j.jamda.2025.105829. Epub ahead of print. PMID: 40882950.
Lavecchia M, Marucci M, Raina P, Jimenez W, Nguyen JMV. Frailty and gynecologic cancer: a cross-sectional analysis of the Canadian Longitudinal Study on Aging. International Journal of Gynecological Cancer. 2025 Jan 17;101642. doi.org/10.1016/j.ijgc.2025.101642