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Publications

Scientific publications using Canadian Longitudinal Study on Aging (CLSA) data.

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Associations between risk of obstructive sleep apnea and cognitive performance In Parkinson’s disease: evidence from the Canadian Longitudinal Study on Aging

Gomes T, Benedetti A, Postuma RB, Lafontaine AL, Kimoff RJ, Kaminska M. Associations between risk of obstructive sleep apnea and cognitive performance In Parkinson’s disease: evidence from the Canadian Longitudinal Study on Aging. Sleep Breath. 2025 Nov 8;29(6):347. doi: 10.1007/s11325-025-03525-7. PMID: 41205061.

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Genetic variations in bitter taste receptors and COVID-19 in the Canadian Longitudinal Study on Aging

Shafizadeh M, Khan MW, Drögemöller B, Stavropoulou C, St John P, Bhullar RP, Chelikani P, Hitchon CA. Genetic Variations in Bitter Taste Receptors and COVID-19 in the Canadian Longitudinal Study on Aging. Biomedicines. 2025 Oct 11;13(10):2473. doi: 10.3390/biomedicines13102473. PMID: 41153757; PMCID: PMC12562077.

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A genome-wide association study identified 10 novel genomic loci associated with intrinsic capacity

Beyene MB, Visvanathan R, Alemu R, Benyamin B, Bhattacharjee R, Beyene HB, Theou O, Cesari M, Beard JR, Amare AT. A genome-wide association study identified 10 novel genomic loci associated with intrinsic capacity. J Gerontol A Biol Sci Med Sci. 2025 Oct 5;80(11):glaf196. doi: 10.1093/gerona/glaf196. PMID: 41066301; PMCID: PMC12510315.

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Cardiovascular risk in aging adults with double deficits in social support: A gender-sensitive, cross-sectional analysis of the CLSA cohort

Conklin AI, Safari A, Veenstra G, Khan NA. Cardiovascular risk in aging adults with double deficits in social support: A gender-sensitive, cross-sectional analysis of the CLSA cohort. PLoS One. 2025 Jun 20;20(6):e0309634. doi: 10.1371/journal.pone.0309634. PMID: 40540518; PMCID: PMC12180724.

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Examining Psychosocial Factors Influencing Nutrition Risk in Middle Aged and Older Adults: Findings from the Canadian Longitudinal Study on Aging

Mills, C. M.; Donnelly, C. Examining Psychosocial Factors Influencing Nutrition Risk in Middle-Aged and Older Adults: Findings from the Canadian Longitudinal Study on Aging. Preprints 2025, 2025072569. https://doi.org/10.20944/preprints202507.2569.v1

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Causal relationships between plasma metabolites and prostate cancer: A Mendelian randomization study exploring immune and inflammatory mediators

Huang M, Ning D, Tong T, Teng Q, Cao F, Guan Y, Wang Y, Lei H, Pang J. Causal relationships between plasma metabolites and prostate cancer: A Mendelian randomization study exploring immune and inflammatory mediators. Current Urology. 2025 Sep 11. DOI: 10.1097/CU9.0000000000000307

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The role of gut microbiota and plasma metabolites in osteoporosis: Insights from Mendelian randomization analysis

Zhu W, Ma S, Zheng X, Yin J. The role of gut microbiota and plasma metabolites in osteoporosis: Insights from Mendelian randomization analysis. Medicine (Baltimore). 2025 Sep 12;104(37):e44409. doi: 10.1097/MD.0000000000044409. PMID: 40958276; PMCID: PMC12440530.

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The Role of Plasma Metabolites in Mediating the Effect of Gut Microbiota on Obstructive Sleep Apnea: A Two-Step, Two-Sample Mendelian Randomization Study

Wang X, Zhao R, Guo J, Yang K, Xu B. The Role of Plasma Metabolites in Mediating the Effect of Gut Microbiota on Obstructive Sleep Apnea: A Two-Step, Two-Sample Mendelian Randomization Study. Nat Sci Sleep. 2025 Sep 3;17:2119-2130. doi: 10.2147/NSS.S527778. PMID: 40927699; PMCID: PMC12415091.

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Unlocking the Secrets: Causal Associations Between Blood Metabolites and Aspergillosis

Ma Y, Du W. Unlocking the Secrets: Causal Associations Between Blood Metabolites and Aspergillosis. Curr Microbiol. 2025 Sep 4;82(10):490. doi: 10.1007/s00284-025-04465-x. PMID: 40906222.

Mendelian randomisation analysis to discover plasma metabolites mediating the effect of obesity on cancer risk

Yates T, Went M, Mills C, Law P, Gockel I, Maj C, Schumacher J, Palles C, Houlston R. Mendelian randomisation analysis to discover plasma metabolites mediating the effect of obesity on cancer risk. Br J Cancer. 2025 Nov;133(9):1344-1353. doi: 10.1038/s41416-025-03170-7. Epub 2025 Sep 2. PMID: 40897820; PMCID: PMC12572173.

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Investigating Causal Links between Metabolite Profiles and Ulcerative Colitis: A Bidirectional Mendelian Randomization Study

Zarei P, Kamali Z, Keshteli AH, Sedeh PA, Vaez A. Investigating Causal Links between Metabolite Profiles and Ulcerative Colitis: A Bidirectional Mendelian Randomization Study. J Med Signals Sens. 2025 Sep 1;15:27. doi: 10.4103/jmss.jmss_16_25. PMID: 40949582; PMCID: PMC12431707.

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Plasma metabolites mediate the effects of circulating immune cell phenotypes on prostate cancer: A 2-step Mendelian randomization study

Zhou W, Ding J, Shen Y, Huang F, Xu D. Plasma metabolites mediate the effects of circulating immune cell phenotypes on prostate cancer: A 2-step Mendelian randomization study. Medicine (Baltimore). 2025 Sep 5;104(36):e44282. doi: 10.1097/MD.0000000000044282. PMID: 40922267; PMCID: PMC12419313.

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The CLSA data are currently available to approved public sector researchers in Canada and elsewhere. Learn more about eligibility and how to apply for access.

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