Vision et santé des yeux

Han X, Steven K, Qassim A, Marshall HN, Bean C, Tremeer M, An J, Siggs OM, Gharahkhani P, Craig JE, Hewitt AW, Trzaskowski M, MacGregor S. Automated AI labeling of optic nerve head enables insights into cross-ancestry glaucoma risk and genetic discovery in >280,000 images from UKB and CLSA. Am J Hum Genet. 2021 Jul 1;108(7):1204-1216. doi: 10.1016/j.ajhg.2021.05.005. Epub 2021 Jun 1. PMID: 34077762; PMCID: PMC8322932.

Samico GA, da Costa DR, Scherer R, Azizi A, Rabinowitz AS, Malek DA, Gracitelli CPB, Medeiros FA. Deep Learning-Predicted RNFL Loss and Incident Glaucoma in the Canadian Longitudinal Study on Aging. Ophthalmol Glaucoma. 2026 Mar 18:S2589-4196(26)00051-7. doi: 10.1016/j.ogla.2026.03.006. Epub ahead of print. PMID: 41862096.

Zhou Y, Wang Z, Huang C, Yu X, Chen J, Jiang X, Dong J, Peng Q, Li L, Song X, Lu X. Gut Microbiota Signatures and Potential Mediators in the Trajectory of Age-related Macular Degeneration: A Phased Atlas by Genetic Inference. Int J Med Sci. 2026 Feb 4;23(3):950-962. doi: 10.7150/ijms.119158. PMID: 41799763; PMCID: PMC12964563.

Azizi A, da Costa DR, Scherer R, Malek DA, Samico GA, Medeiros FA. RNFL Thickness in a Population-Based Cohort: The Canadian Longitudinal Study on Aging M2M (Machine-to-Machine) Study. Am J Ophthalmol. 2025 Oct 4:S0002-9394(25)00530-6. doi: 10.1016/j.ajo.2025.09.051. Epub ahead of print. PMID: 41052566.

O’Neil A, Welikala RA, Barman S, Owen CG, Rudnicka AR, Rakesh M, Roy-Gagnon MH, Maberley D, Freeman EE. Retinal Vessel Traits and Age-Related Eye Disease in the Canadian Longitudinal Study on Aging. Clin Exp Ophthalmol. 2025 Jun 14. doi: 10.1111/ceo.14566. Epub ahead of print. PMID: 40515626.

Tran E, Rakesh M, Li G, Freeman EE, Roy-Gagnon MH. Does the Association Between Eye Disease and Cognitive Function Vary by Genetic Risk of Cognitive Decline? An Analysis of Hospital Data With Replication in the Canadian Longitudinal Study on Aging. Invest Ophthalmol Vis Sci. 2025 Jun 2;66(6):71. doi: 10.1167/iovs.66.6.71. PMID: 40548629; PMCID: PMC12186830.

Jiang X, Mahroo OA, Khawaja AP, Skowronska-Krawczyk D, Mackey DA, Wiggs JL, Hammond CJ, Hysi PG, Bell CG. Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging. Epigenetics. 2025 Dec;20(1):2566496. doi: 10.1080/15592294.2025.2566496. Epub 2025 Oct 17. PMID: 41105805; PMCID: PMC12536625.

O’Neil A, Welikala RA, Barman S, Owen CG, Rudnicka AR, Rakesh M, Roy-Gagnon MH, Maberley D, Freeman EE. Retinal Vessel Traits and Age-Related Eye Disease in the Canadian Longitudinal Study on Aging. Clin Exp Ophthalmol. 2025 Jun 14. doi: 10.1111/ceo.14566. Epub ahead of print. PMID: 40515626.

Lepetit-Aimon G, Mameri L, Duval R, Cheriet F. Enhanced Graph Representation for Reliable Retinal Vessel Analysis: CLSA Population-Based Study, 2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI), 2025, pp. 1-5, doi: 10.1109/ISBI60581.2025.10981176.

O’Neil A, Welikala RA, Barman S, Owen CG, Rudnicka AR, Rakesh M, Roy-Gagnon MH, Maberley D, Freeman EE. Factors Associated With Retinal Vessel Traits in the Canadian Longitudinal Study on Aging. Invest Ophthalmol Vis Sci. 2025 Mar 3;66(3):13. doi: 10.1167/iovs.66.3.13. PMID: 40048189; PMCID: PMC11895846.

Lelievre R, Rakesh M, Hysi PG, Little J, Freeman EE, Roy-Gagnon MH. Evaluating vitamin C-related gene-environment and metabolite-environment interaction effects on intraocular pressure in the Canadian Longitudinal Study on Aging. BMC Genom Data. 2025 Jan 29;26(1):10. doi: 10.1186/s12863-025-01301-w. PMID: 39881263; PMCID: PMC11776179.

Iverson E, Sukhai M, Quinn MP, Aubin MJ, Freeman EE. Visual impairment, employment status, and reduction in income: the Canadian Longitudinal Study on Aging. Can J Ophthalmol. 2024 May 23:S0008-4182(24)00131-5. doi: 10.1016/j.jcjo.2024.04.006. Epub ahead of print. PMID: 38797511.