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2025

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Association between modifiable risk factors and cognitive decline in people over the age of 45 with polypharmacy

Polypharmacy, which is prevalent in older adults, is linked to adverse drug reactions, a...

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Predicting hearing loss using machine learning

Hearing decline is a common complaint among older adults. Aging affects an individual’s hearing...

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Relationships between psycho-socio-economic factors and the prevalence and incidence of cardiorenal multimorbidity in the Canadian population: inter-relationship with physical activity and fitness

Kidney disease and heart disease are major health challenges in Canada, and often occur...

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Understanding pathways linking arthritis to changes in health, activities, and participation and overall well-being

Healthy aging is variably defined but dominated by a focus on disability, particularly in...

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Comprehensive prediction of osteoporotic fractures through machine learning and DXA imaging

Osteoporosis is a common condition in older adults, leading to weakened bones and increased...

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Association of early-life growth conditions with adult lung health

Early-life growth conditions have been associated with later-life lung health and disease. Whether this...

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Using capture-recapture methodologies to estimate the prevalence of undetected dementia in Ontario

The rising prevalence of dementia is a prominent population and public health challenge. Evidence...

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Identifying and predicting trajectories of decline in cognitive and physical function using data from Canadian Longitudinal Study of Aging (CLSA) linked to routinely collected health system data

Trajectories of cognitive decline and patterns of health care utilization and costs. There are...

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Ontario health menopause quality standard

The purpose of this request for CLSA data access is to support the quality...

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Daily activities and positive and negative mental health in the Canadian population

Using a two-factor model, this project will explore mental health in older adults by...

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Evaluating the progression of multidimensional frailty in the Canadian population

Frailty, especially at its earlier stages, may represent a period of transition from healthy...

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Cognitive trajectories and dementia risk in individuals with subjective cognitive decline

This study focuses on subjective cognitive decline (SCD), where people notice memory issues despite...

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