Degenerative protein modifications (DPMs) as molecular mediators connecting socio-demographic profile to the onset of age-related diseases We have identified a set of degenerative protein modifications (DPMs) in patients’ tissues, resulting... Learn More
Identification of genetic variants associated with frailty – a genome-wide association study The world population is getting older, and we are observing the same phenomenon in... Learn More
Trajectories of work productivity loss: working from home and insights during COVID-19 People with health problems may attend at work with reduced productivity (presenteeism), take sick... Learn More
Examining social inequalities in caregiver well-being: an analysis of CLSA data on caregiving across levels of social stratification In Canada, a significant percentage of seniors served as caregivers, with gender differences observed... Learn More
Cross-lagged associations between social connections and physical activity in older adults: understanding synergies and direction of effects Physical activity (PA) and positive social connections are important for well-being, but physical inactivity... Learn More
Identify underlying pathways and characterize key moderators of the higher life satisfaction and lower mortality risk association In light of our nation’s 1) rapidly ageing population, 2) rising medical costs, and... Learn More
Death and dying in Canada – an analysis of the Decedent Questionnaire of the CLSA The place of death for most older Canadians has changed over time, but most... Learn More
A causal inference approach to life satisfaction and outcome-wide health The biopsychosocial model of health emphasizes the importance of patients’ well-being in determining their... Learn More
Adverse childhood experiences, genomic influences, and acceleration of biological aging in middle-aged and older adults in the CLSA Adverse childhood experiences (ACEs), including childhood exposure to abuse, neglect, and intimate partner violence... Learn More
Influenza, pneumococcal, shingles, and COVID-19 vaccinations among immigrant and non-immigrant older adults in Canada Older adults are recommended to receive the influenza, pneumococcal, shingles, and COVID-19 vaccines, as... Learn More
Interactive visualization of genetic variant-trait associations in the CLSA dataset The CLSA study collected data on thousands of traits and hundreds of millions of... Learn More
Reference values and the psychometric properties of the Life-Space Assessment in the Canadian Longitudinal Study on Aging The Life-Space Assessment (LSA) is a questionnaire that measures everyday mobility. It assesses the... Learn More