Multi-organ functional ageing in the CLSA: Longitudinal phenotypes, omics, and mortality We age in different ways. Some people lose strength or walking speed quickly; others... Learn More
Multi-omics integrated analysis of obesity-related osteoarthritis People who carry excess body weight have a much higher risk of developing osteoarthritis... Learn More
Using multi-omics to predict chronic diseases outcomes As people age, the risk od developing chronic diseases increases, including sarcopenia, cancer, obesity,... Learn More
Diet and 6-year muscle and cognitive function trajectories in the Canadian Longitudinal Study on Aging: combining traditional and omics approaches While heart health studies recommend eating more plant-based proteins, healthy aging studies highlight the... Learn More
Multi-omics determinants underlying dementia susceptibility Our research aims to protect people’s brains from dementia, a condition that causes memory... Learn More
Using metabolomics to examine the association between diet, inflammation, and frailty in the Canadian Longitudinal Study on Aging (CLSA) Frailty is a condition where our bodies become less resilient and struggle to cope... Learn More
Investigation of the aging process – a multi-omics approach The rate of aging varies from individual to individual due to several factors, including... Learn More
Biological dysregulation as a mechanism of unhealthy aging in older adults Evidence suggests that a breakdown of the numerous biological systems that maintain good health... Learn More
Degenerative protein modifications (DPMs) as molecular mediators connecting socio-demographic profile to the onset of age-related diseases We have identified a set of degenerative protein modifications (DPMs) in patients’ tissues, resulting... Learn More
Adverse childhood experiences, genomic influences, and acceleration of biological aging in middle-aged and older adults in the CLSA Adverse childhood experiences (ACEs), including childhood exposure to abuse, neglect, and intimate partner violence... Learn More
Canadian Longitudinal Study on Aging (CLSA): building a COVID-19 platform for research in Canada Learn More
