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genomics

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Using multi-omics to predict chronic diseases outcomes

As people age, the risk od developing chronic diseases increases, including sarcopenia, cancer, obesity,...

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Multi-omics kidney aging trajectories across environments

Premature aging involves harmful changes in the body over time, increasing disease risk. The...

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Diet and 6-year muscle and cognitive function trajectories in the Canadian Longitudinal Study on Aging: combining traditional and omics approaches

While heart health studies recommend eating more plant-based proteins, healthy aging studies highlight the...

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Multi-omics determinants underlying dementia susceptibility

Our research aims to protect people’s brains from dementia, a condition that causes memory...

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Investigating the associations between ambient air pollution exposure and genomics, epigenomics and metabolomics

Cancer and other age-related diseases are known to be associated with high air pollution...

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Investigation of the aging process – a multi-omics approach

The rate of aging varies from individual to individual due to several factors, including...

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Degenerative protein modifications (DPMs) as molecular mediators connecting socio-demographic profile to the onset of age-related diseases

We have identified a set of degenerative protein modifications (DPMs) in patients’ tissues, resulting...

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Identification of genetic variants associated with frailty – a genome-wide association study

The world population is getting older, and we are observing the same phenomenon in...

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Interactive visualization of genetic variant-trait associations in the CLSA dataset

The CLSA study collected data on thousands of traits and hundreds of millions of...

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Identifying novel genetic factors predisposing to inherited cardiac disorders

Inherited cardiac disorders arise from genetic variations and can manifest as cardiomyopathies or arrhythmic...

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Identification and statistical analysis for risk factors for vision loss and bone loss by joint analysis of genetic, imaging and biomedical data

Vision loss and bone loss are two major disorders in older adults because of...

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Identifying genetic risk variants and developing a deep learning prediction model for disability development in the elderly: a study using the Canadian Longitudinal Study on Aging

Disability in the elderly is a significant health issue with a growing impact on...

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