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genetics

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Construction and validation of an FTO gene-wide risk score for research into gene-environment interactions and obesity

Obesity manifests from interactions between genetic variants and environmental factors. The fat mass and...

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Genetic analyses of healthy aging: buffering and exploratory analyses

Genetic variants are like spelling differences in genes. Genetic buffering is when a variant...

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Identification of genetic variants associated with frailty – a genome-wide association study

The world population is getting older, and we are observing the same phenomenon in...

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Adverse childhood experiences, genomic influences, and acceleration of biological aging in middle-aged and older adults in the CLSA

Adverse childhood experiences (ACEs), including childhood exposure to abuse, neglect, and intimate partner violence...

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Predicting clinical manifestations of Parkinson’s Disease using polygenic risk scores

People living with Parkinson’s disease experience a variety of symptoms including problems with movement,...

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Bitter taste receptors and COVID-19

Proteins that help taste sensation (bitter taste receptors or T2Rs) have recently been shown...

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An investigation into the genetic basis of human intrinsic capacity

The World Health Organization (WHO) has reframed the definition of healthy aging as the...

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Genetic analyses of mental health trajectories in aging adults

As people age, changes in mental health can occur. The genetic and environmental factors...

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Investigating the interplay between genetics, social, and environmental factors in nutrition, aging, and health in the CLSA

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Cognitive aging in middle and older-aged Canadians: consideration of genetic risk, modifiable factors, and biological sex

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Understanding the genetic and environmental determinants of metabolism- and aging-related phenotypes

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Canadian Longitudinal Study on Aging (CLSA): building a COVID-19 platform for research in Canada

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