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frailty

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Managing and AVOIDing frailty and adverse musculoskeletal health among Canadian males and females

Canada’s population is facing rising rates of frailty, where weakened bodily systems reduce resilience....

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Associations between adverse childhood experiences, intimate partner violence, and elder abuse and health outcomes: results from the Canadian Longitudinal Study on Aging

Adverse childhood experiences (ACEs), intimate partner violence (IPV), and elder abuse (EA) are public...

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Evaluating the progression of multidimensional frailty in the Canadian population

Frailty, especially at its earlier stages, may represent a period of transition from healthy...

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The longitudinal, prospective association between diabetes and frailty among middle-aged and older adults in Canada

Diabetes mellitus (DM) is a chronic disease that affects 10% of Canadians. It classically...

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Digging deeper: factors that modify and/or mediate sensory-cognitive associations in the CLSA

Cognitive decline (which is a normal part of aging) and dementia (which is an...

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Frailty in older adults with multiple sclerosis (MS): investigating associations with psychological health and lifestyle factors

The intersection of multiple sclerosis (MS) and aging presents unique challenges as it combines...

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Frailty in survivors of cancer – exploring rehabilitation to improve frailty outcomes (REHAB-FIC)

Although both frailty and cancer can occur at any age, they are predominantly seen...

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Using metabolomics to examine the association between diet, inflammation, and frailty in the Canadian Longitudinal Study on Aging (CLSA)

Frailty is a condition where our bodies become less resilient and struggle to cope...

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Health deficit accumulation in relation to cardiovascular disease burden

Frailty in cardiovascular disease is a problem related to poor quality of life, hospital...

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Biological dysregulation as a mechanism of unhealthy aging in older adults

Evidence suggests that a breakdown of the numerous biological systems that maintain good health...

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Identification of genetic variants associated with frailty – a genome-wide association study

The world population is getting older, and we are observing the same phenomenon in...

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Broad and deep longitudinal analysis in neurodegenerative disease (BRAIN): Identifying and predicting trajectories of decline in cognitive and physical function using data from CLSA linked to routinely collected health system data (follow-up)

Declines in various aspects of cognition such as memory, language skills and reasoning are...

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