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Investigating the associations between ambient air pollution exposure and genomics, epigenomics and metabolomics

Cancer and other age-related diseases are known to be associated with high air pollution...

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Genetic analyses of healthy aging: buffering and exploratory analyses

Genetic variants are like spelling differences in genes. Genetic buffering is when a variant...

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Investigation of the aging process – a multi-omics approach

The rate of aging varies from individual to individual due to several factors, including...

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Biological dysregulation as a mechanism of unhealthy aging in older adults

Evidence suggests that a breakdown of the numerous biological systems that maintain good health...

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Evaluating clonal haematopoiesis in CLSA

Somatic mutations become common as people age. These somatic mutations have been implicated in...

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Longitudinal effects of nutritional and sociodemographic determinants on healthy aging – lessons to learn from the Canadian Longitudinal Study on Aging

Healthy aging is a main concern worldwide. Understanding the factors that affect it is...

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Mediation of the relationship between age and cognition by stroke and vascular risk factors: an analysis of the Canadian Longitudinal Study on Aging

Dementia is one of the largest public health crises of our time. With increasing...

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Using artificial intelligence to predict cardiac age and its impact on health

As we age, our functional abilities decline, but the rate of decline varies among...

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Reference values and the psychometric properties of the Life-Space Assessment in the Canadian Longitudinal Study on Aging

The Life-Space Assessment (LSA) is a questionnaire that measures everyday mobility. It assesses the...

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Understanding the social determinants of healthy ageing – a multinational longitudinal cohort comparison study

Social determinants of health (SDH) refer to the social, economic, and environmental conditions in...

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Hypothetical interventions for real world impact: addressing the obesity epidemic in older adults

The Canadian population is aging rapidly and older adults represent the fastest growing part...

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An assessment of the impact of transport opportunities and barriers for the aging Canadian population

Mobility is linked to health status and quality of life. However, the Canadian transportation...

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