Mendelian randomization study implicates inflammaging biomarkers in retinal vasculature, cardiovascular diseases, and longevity

Villaplana-Velasco A, Perrot N, Hang Y, Chong M, Trucco E, Mookiah MRK, Nelson W, Petch J, Gerstein HC, Raina P, Yusuf S, Bernabeu MO, Tenesa A, Rawlik K, Pare G, Doney A, Pairo-Castineira E, Pigeyre M. Mendelian randomization study implicates inflammaging biomarkers in retinal vasculature, cardiovascular diseases, and longevity. Sci Adv. 2025 Oct 24;11(43):eadu1985. doi: 10.1126/sciadv.adu1985. Epub 2025 Oct 24. PMID: 41134885; PMCID: PMC12551708.

Coverage of the influenza and pneumococcal vaccinations among immigrant and non-immigrant older adults in Canada: a cross-sectional analysis of data from the Canadian Longitudinal Study on Aging (CLSA)

Kim JY, Sulis G, Russell A, Yang S, Papenburg J, Banerjee A, Li P. Coverage of the influenza and pneumococcal vaccinations among immigrant and non-immigrant older adults in Canada: a cross-sectional analysis of data from the Canadian Longitudinal Study on Aging (CLSA). BMC Public Health. 2025 Nov 4;25(1):3775. doi: 10.1186/s12889-025-25005-z. PMID: 41188807; PMCID: PMC12584234.

Association Between Menopause Age and Estradiol-Based Hormone Therapy With Cognitive Performance in Cognitively Normal Women in the CLSA

Puri TA, Gravelsins LL, Alexander MW, McGovern AJ, Guterman PD, Rabin JS, Murphy KJ, Galea LAM. Association Between Menopause Age and Estradiol-Based Hormone Therapy With Cognitive Performance in Cognitively Normal Women in the CLSA. Neurology. 2025 Sep 23;105(6):e213995. doi: 10.1212/WNL.0000000000213995. Epub 2025 Aug 27. PMID: 40865026; PMCID: PMC12380479.

Modification effect of polygenic risk scores on the risk of the most common multimorbidity associated with aging among Canadian adults: An analysis of the CLSA data

Mortey O, Mugford G, Aubrey-Bassler K, Mariathas HH, Odimba U, Gao Z. Modification effect of polygenic risk scores on the risk of the most common multimorbidity associated with aging among Canadian adults: An analysis of the CLSA data. Arch Gerontol Geriatr. 2025 Nov;138:105992. doi: 10.1016/j.archger.2025.105992. Epub 2025 Aug 16. PMID: 40845754.

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