Shi H, Peng Q. Role of metabolites in mediating the effect of gut microbiota on Crohn disease: A two-step Mendelian randomization (MR) study. Medicine (Baltimore). 2025 Nov 28;104(48):e46253. doi: 10.1097/MD.0000000000046253. PMID: 41327678; PMCID: PMC12662486.