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Genome-wide meta-analysis

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Inflammatory proteins mediate male erectile dysfunction via plasma metabolites 

Kang Z, Zhang ZR, Feng ZY, Dong LS, Yang J. Inflammatory proteins mediate male erectile dysfunction via plasma metabolites. Sex Med. 2024 May 31;12(3):qfae027. doi: 10.1093/sexmed/qfae027. PMID: 38827362; PMCID: PMC11140220.

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Exploring the Mediation Effect of Metabolite Levels on the Association Between Gut Microbiota and HCC: A two-step, two-sample bidirectional Mendelian Randomization

Xu B, Zhu L, Hu P, Yao W, Ke M, Zhu Z. Exploring the Mediation Effect of Metabolite Levels on the Association Between Gut Microbiota and HCC: A two-step, two-sample bidirectional Mendelian Randomization. J Cancer. 2024 May 30;15(12):3975-3983. doi: 10.7150/jca.96579. PMID: 38911378; PMCID: PMC11190768.

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Blood metabolites and chronic kidney disease: a Mendelian randomization study

Hou Y, Xiao Z, Zhu Y, Li Y, Liu Q, Wang Z. Blood metabolites and chronic kidney disease: a Mendelian randomization study. BMC Med Genomics. 2024. May 20 2024;17:147. doi: 10.1186/s12920-024-01918-3.

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Causal relationships of gut microbiota, plasma metabolites, and metabolite ratios with diffuse large B-cell lymphoma: a Mendelian randomization study

Qian J, Zheng W, Fang J, Cheng S, Zhang Y, Zhuang X, Song C. Causal relationships of gut microbiota, plasma metabolites, and metabolite ratios with diffuse large B-cell lymphoma: a Mendelian randomization study. Front Microbiol. 2024 May 27;15:1356437. doi: 10.3389/fmicb.2024.1356437. PMID: 38860219; PMCID: PMC11163048.

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Polygenic Prediction of Keratoconus and its Measures: Cross-Sectional and Longitudinal Analyses in Community-Based Young Adults

Lee SS, Diaz-Torres S, He W, Yazar S, Chan E, Chong EW, Gharahkhani P, Macgregor S, Lingham G, Mackey DA. Polygenic Prediction of Keratoconus and its Measures: Cross-Sectional and Longitudinal Analyses in Community-Based Young Adults. Am J Ophthalmol. 2024 May 11;265:248-256. doi: 10.1016/j.ajo.2024.05.009. Epub ahead of print. PMID: 38740237.

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Genome-wide meta-analysis identifies novel loci and improves disease prediction of age-related macular degeneration

He W, Han X, Ong JS, Wu Y, Hewitt AW, Mackey DA, Gharahkhani P, MacGregor S. Genome-wide meta-analysis identifies novel loci and improves disease prediction of age-related macular degeneration. Ophthalmology. 2023 Aug 25:S0161-6420(23)00622-X. doi: 10.1016/j.ophtha.2023.08.023. Epub ahead of print. PMID: 37634759.

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