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Genetics

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Associations between human blood metabolome and risk of myocarditis: a Mendelian randomization study

Wang Z, Tian H, Wang J. Association between human blood metabolome and risk of myocarditis: a mendelian randomization study. Sci Rep. 2024 Nov 3;14(1):26494. doi: 10.1038/s41598-024-78359-6. PMID: 39489852; PMCID: PMC11532538.

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Blood metabolites as predictors of skin cancer risk: a comprehensive analysis

Wu K, He Y, Hua A, Yao Y. Blood metabolites as predictors of skin cancer risk: a comprehensive analysis. Postępy Higieny i Medycyny Doświadczalnej. 2024 Aug 18;78(1). DOI: https://doi.org/10.2478/ahem-2004-0007

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Assessing the casual relationship between metabolic biomarkers and coronary artery disease by Mendelian randomization studies

Yang K, Li J, Hui X, Wang W, Liu Y. Assessing the causal relationship between metabolic biomarkers and coronary artery disease by Mendelian randomization studies. Sci Rep. 2024 Aug 16;14(1):19034. doi: 10.1038/s41598-024-69879-2. PMID: 39152174; PMCID: PMC11329738.

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Multi-omics insight into the metabolic and cellular characteristics in the pathogenesis of hypothyroidism

Zheng S, Liu L, Liang K, Yan J, Meng D, Liu Z, Tian S, Shan Y. Multi-omics insight into the metabolic and cellular characteristics in the pathogenesis of hypothyroidism. Commun Biol. 2024 Aug 14;7(1):990. doi: 10.1038/s42003-024-06680-x. PMID: 39143378; PMCID: PMC11324791.

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Causality of genetic determined metabolites and metabolic pathways on osteoarthritis: a two-sample mendelian randomization study

Gu Y, Jin Q, Hu J, Wang X, Yu W, Wang Z, Wang C, Liu Y, Chen Y, Yuan W. Causality of genetically determined metabolites and metabolic pathways on osteoarthritis: a two-sample mendelian randomization study. J Transl Med. 2023 May 31;21(1):357. doi: 10.1186/s12967-023-04165-9. PMID: 37259122; PMCID: PMC10230782.

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Explore the genetic exposure to alopecia areata

Peng S, Yang Y, Man Y, Long D, Wang L, Li K, Liu P. Explore the genetic exposure to alopecia areata. Skin Res Technol. 2024 Aug;30(8):e13874. doi: 10.1111/srt.13874. PMID: 39086160; PMCID: PMC11291861.

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Casual effects of genetically determined blood metabolites on asthma: a bidirectional Mendelian randomization study

Lin L, Wu Z, Zhong A, Luo H, Xu W, Luo W. Causal effects of genetically determined blood metabolites on asthma: a bidirectional Mendelian randomization study. J Asthma. 2024 Aug 1:1-11. doi: 10.1080/02770903.2024.2380515. Epub ahead of print. PMID: 39087774.

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Genomic Analysis Identifies Risk Factors in Restless Legs Syndrome

Akçimen F, Chia R, Saez-Atienzar S, Ruffo P, Rasheed M, Ross JP, Liao C, Ray A, Dion PA, Scholz SW, Rouleau GA, Traynor BJ. Genomic Analysis Identifies Risk Factors in Restless Legs Syndrome. Ann Neurol. 2024 Jul 30. doi: 10.1002/ana.27040. Epub ahead of print. PMID: 39078117.

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Casual relationships between immune cells, inflammatory factors, serum metabolites, and hepatic cancer: A two-sample Mendelian randomization study

Chen H, Yang R, Zhang J, Tang J, Yu X, Zhou W, Li K, Peng W, Zeng P. Casual relationships between immune cells, inflammatory factors, serum metabolites and hepatic cancer: A two-sample Mendelian randomization study. Heliyon. 2024 Jul 23

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Role of blood metabolites in mediating the effect of gut microbiome on the mutated-RAS/BRAF metastatic colorectal cancer-specific survival

Xiang Y, Zhang C, Wang J, Cheng Y, Wang K, Wang L, Tong Y, Yan D. Role of blood metabolites in mediating the effect of gut microbiome on the mutated-RAS/BRAF metastatic colorectal cancer-specific survival. Int J Colorectal Dis. 2024 Jul 24;39(1):116. doi: 10.1007/s00384-024-04686-9. PMID: 39046546; PMCID: PMC11269474.

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Mediating role of chiro-inositol metabolites on the effects of HLA-DR-expressing CD14 + monocytes in inflammatory bowel disease

Zhang L, Shen P, Ge W, Liao W, Luo Q, Li C, Zhan C, Yuan X, Zhang X, Yan X. Mediating role of chiro-inositol metabolites on the effects of HLA-DR-expressing CD14 + monocytes in inflammatory bowel disease. BMC Gastroenterol. 2024 Jun 17;24(1):200. doi: 10.1186/s12876-024-03271-2. PMID: 38886630; PMCID: PMC11181584.

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Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression

Zhukovsky P, Tio ES, Coughlan G, Bennett DA, Wang Y, Hohman TJ, Pizzagalli DA, Mulsant BH, Voineskos AN, Felsky D. Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression. Nat Commun. 2024 Jun 18;15(1):5207. doi: 10.1038/s41467-024-49430-7. PMID: 38890310; PMCID: PMC11189393.

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