Génétique

Li G, Qu B, Zheng T, Cheng Y, Li P, Liu Z, Zhao J. Assessing the causal effect of genetically predicted metabolites and metabolic pathways on vitiligo: Evidence from Mendelian randomization and animal experiments. J Steroid Biochem Mol Biol. 2025 Mar;247:106677. doi: 10.1016/j.jsbmb.2025.106677. Epub 2025 Jan 14. PMID: 39818343.

Li Y, Song X, Huang Y, Zhou S, Zhong L. Genetic associations of plasma metabolites with immune cells in hyperthyroidism revealed by Mendelian randomization and GWAS-sc-eQTLs xQTLbiolinks analysis. Sci Rep. 2025 Jan 8;15(1):1377. doi: 10.1038/s41598-025-85664-1. PMID: 39779799; PMCID: PMC11711443.

Yang B, Li Z, Li P, Liang B, Liu Y, Feng E. Role of T cell metabolism in brain tumor development: a genetic and metabolic approach. BMC Neurol. 2025 Jan 8;25(1):12. doi: 10.1186/s12883-024-04015-1. PMID: 39780065; PMCID: PMC11708232.

Li M, Zhang Q, Wu T, Ma L, Hu D, Yuan Z, Wang S, Luo A, Zhang J. How does gut microbiota affect the vaginitis axis? The mediating role of plasma metabolites. Microbiol Spectr. 2025 Feb 4;13(2):e0226324. doi: 10.1128/spectrum.02263-24. Epub 2024 Dec 31. PMID: 39745427; PMCID: PMC11792462.

He Y, Cai P, Hu A, Li J, Li X, Dang Y. The role of 1400 plasma metabolites in gastric cancer: A bidirectional Mendelian randomization study and metabolic pathway analysis. Medicine (Baltimore). 2024 Nov 29;103(48):e40612. doi: 10.1097/MD.0000000000040612. PMID: 39612432; PMCID: PMC11608735.

Zhang J, Chen H, Yang R, Tang J, Yu X, Zeng P, Peng W. Association between immune cell attributes, serum metabolites, inflammatory protein factors, and colorectal cancer: A Mendelian randomization study. Medicine (Baltimore). 2024 Nov 29;103(48):e40691. doi: 10.1097/MD.0000000000040691. PMID: 39612465; PMCID: PMC11608676.

Liu ZY, Zhang H, Sun XL, Liu JY. Causal association between metabolites and age-related macular degeneration: a bidirectional two-sample mendelian randomization study. Hereditas. 2024 Dec 20;161(1):51. doi: 10.1186/s41065-024-00356-6. PMID: 39707561; PMCID: PMC11662531.

Qi W, Mao X, Mei Z, Zhu L, Shao Y, Ge G, Jia G, Pan H, Wang D. Causal Relationship Between Circulating Metabolites and Sarcopenia-Related Traits: A Mendelian Randomization and Experimental Study. Food Sci Nutr. 2025 Jan 9;13(1):e4624. doi: 10.1002/fsn3.4624. PMID: 39803274; PMCID: PMC11717068.

Lou J, Tu M, Xu M, Cao Z, Song W. Plasma pQTL and brain eQTL integration identifies PNKP as a therapeutic target and reveals mechanistic insights into migraine pathophysiology. J Headache Pain. 2024 Nov 22;25(1):202. doi: 10.1186/s10194-024-01922-z. PMID: 39578729; PMCID: PMC11585170.

Shi Y, Qin J, Li Y, Yang J, Lu Y. Type 1 Diabetes and Cataracts: Investigating Mediating Effects of Serum Metabolites Using Bidirectional Mendelian Randomization. Metabolites. 2024 Nov 20;14(11):644. doi: 10.3390/metabo14110644. PMID: 39590881; PMCID: PMC11596039.

Cui Y, Wang H, Wang Y. Plasma metabolites as mediators in the relationship between inflammation-related proteins and benign prostatic hyperplasia : insights from mendelian randomization. Sci Rep. 2024 Oct 30 ; 14(1):26152. doi : 10.1038/s41598-024-77515-2. PMID : 39478098 ; PMCID : PMC11525667.

Cao D, Zhang Y, Zhang S, Li J, Yang Q, Wang P. Risk of Alzheimer’s disease and genetically predicted levels of 1400 plasma metabolites: a Mendelian randomization study. Sci Rep. 2024 Oct 30;14(1):26078. doi: 10.1038/s41598-024-77921-6. PMID: 39478193; PMCID: PMC11525545.