Génétique

Rivera-Herrera AL, Rouleau M, Singbo MNU, Cuppens T, Carmichael PH, Droit A, Simonyan D, Laurin D, Guillemette C. Exploration de l’association entre les délétions génétiques courantes et le vieillissement : enseignements tirés de l’Étude longitudinale canadienne sur le vieillissement. Geroscience. 24 juin 2026. doi : 10.1007/s11357-026-02363-z. Publication en ligne avant impression. PMID : 42340576.

Ingold N, Seviiri M, Ong JS, Gordon S, Neale RE, Whiteman DC, Olsen CM, MacGregor S, Law MH. Genetic Analysis of Perceived Youthfulness Reveals Differences in How Men’s and Women’s Age Is Assessed. J Invest Dermatol. 2024 Mar 7:S0022-202X(24)00180-5. doi: 10.1016/j.jid.2024.02.019. Epub ahead of print. PMID: 38460809.

Yang Y, Li T, Jing W, Qin W, Yang Q. Causal effects of gut microbiota on schizophrenia: deciphering profiles mediated by cerebrospinal fluid metabolites in the gut-brain axis. World J Biol Psychiatry. 2026 Apr 20:1-17. doi: 10.1080/15622975.2026.2658098. Epub ahead of print. PMID: 42008635.

Gao Y, Ma J, Zhou J, Zhao L, Shi Y, Zhao X. Causal relationships between Burkholderiales, Eubacteriaceae and colorectal cancer mediated by plasma metabolites. Rev Argent Microbiol. 2026 Apr 16;58(3):100719. doi: 10.1016/j.ram.2026.100719. Epub ahead of print. PMID: 41997092.

Wang Q, Lu S. Mapping the genetically predicted associations of plasma metabolites with sarcopenia and aging traits: Evidence from bidirectional Mendelian randomization and transcriptome analysis. J Nutr Biochem. 2026 Apr 1:110362. doi: 10.1016/j.jnutbio.2026.110362. Epub ahead of print. PMID: 41932624.

Xiao Z, Wu Z, Chen Z, Xu Z, Zhou Q, Liu S, Wang M, Hou S, Liu W, Li Z, Xun K, Zhang N, Wang C. Anxiety Disorder Types From a Metabolomics Perspective: A Mendelian Randomization Analysis Based on 1400 Plasma Metabolites. Brain Behav. 2026 Apr;16(4):e71356. doi: 10.1002/brb3.71356. PMID: 41904807.

Zhang M, Liu H, Cao W, Fan L. Causal associations between chronic obstructive pulmonary disease, pulmonary tuberculosis, asthma, and plasma metabolites: A bidirectional Mendelian randomization study. Respir Med. 2026 Mar 24;256:108785. doi: 10.1016/j.rmed.2026.108785. Epub ahead of print. PMID: 41887373.

Zheng X, Xu J, Yin J, Fan J, Gong Y, Yang J. Causal links between gut microbiota, plasma metabolites, and insomnia: Insights from Mendelian randomization. Dialogues Clin Neurosci. 2026 Dec;28(1):85-94. doi: 10.1080/19585969.2026.2636470. Epub 2026 Feb 27. PMID: 41760581; PMCID: PMC12951660.

Liu S, Ma J, Li Z, Li M, Wang T, Yao T, Liu G. Explore the potential mediating role of plasma metabolites and cytokines in the causal relationship between gut microbiota and the severity of immune-related adverse events: A Mendelian randomization study. Medicine (Baltimore). 2026 Feb 27;105(9):e47916. doi: 10.1097/MD.0000000000047916. PMID: 41760011; PMCID: PMC12956236.

Wei Qiuyu, Yu Shaoyong, Zhou Zheyi, Wu Gang . Causal relationship between plasma metabolites and osteonecrosis: a large sample analysis based on genome-wide association study database and FinnGen database[J]. Chinese Journal of Tissue Engineering Research, 2026, 30(29): 7732-7738.

Wang JL, Zhao Q, Zheng R, Fang Y, Cao J, Zhang BR. Cerebrospinal fluid and plasma metabolites in Parkinson’s disease: a Mendelian randomization study. Sci Rep. 2026 Mar 23;16(1):9588. doi: 10.1038/s41598-025-30521-4. PMID: 41872227.

Zhou Y, Wang Z, Huang C, Yu X, Chen J, Jiang X, Dong J, Peng Q, Li L, Song X, Lu X. Gut Microbiota Signatures and Potential Mediators in the Trajectory of Age-related Macular Degeneration: A Phased Atlas by Genetic Inference. Int J Med Sci. 2026 Feb 4;23(3):950-962. doi: 10.7150/ijms.119158. PMID: 41799763; PMCID: PMC12964563.