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Approved Projects

CLSA approved projects encompass a broad spectrum of research topics and questions aimed at comprehensively understanding the aging process and its impact on health and well-being.

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The interplay of polygenic risk scores, lifestyle behaviors, anxiety, and depression progression amid COVID-19 waves: a comprehensive genomic and behavioral analysis of the Canadian Longitudinal Study on Aging

This study delves into the intricate interplay of genetic predispositions, lifestyle behaviors, and the...

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Influence of health behaviours on life satisfaction of Canadian older adults: a secondary data analysis of the Canadian Longitudinal Study on Aging

As the population of older Canadians (65 years and above) continues to grow, it...

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Impact of cognitive reserve indicators on cognition in middle-aged and older adults in waves 1, 2, and 3 of the CLSA

Dementia is characterized by severe, progressive cognitive decline. Alzheimer’s disease, the most common cause...

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Sex, metabolic profiles and alcohol: evaluating prognostic significance steatosis liver disease classifications in the Canadian Longitudinal Study on Aging (CLSA)

Steatotic liver disease (SLD), previously known as fatty liver disease, is the most common...

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The significance of new onset anxiety on health outcomes among women with cardiovascular disease: a Canadian Longitudinal Study of Aging cohort study

Females report the most severe anxiety symptoms post-cardiac event and demonstrate poorer prognoses than...

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Health or wealth? Socioeconomic status as a moderator of the association between healthy activity behaviours and cognitive function

Engaging in physical activity, reducing sedentary behaviour (e.g., sitting), and getting sleep can promote...

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Aging exceptionally well: identifying and characterizing “SuperAgers” in the Canadian Longitudinal Study on Aging database

As baby boomers age, Canada must develop strategies to help individuals age well and...

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Sex differences in the association between vascular risk factors and cognitive decline and the impact of menopause and hormonotherapy

Given that there is still no treatment for Alzheimer’s disease, studying its prevention is...

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Examining the relationship between loneliness, depression, and life satisfaction among Canadian older adults

Canadian older adults experience both symptoms of depression and feelings of loneliness. A positive...

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A factor analytic investigation of allostatic load and associations with cognitive performance

Allostatic load (AL) reflects wear-and-tear from long-term stress, impacting several physiological systems in the...

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The longitudinal, prospective association between diabetes and frailty among middle-aged and older adults in Canada

Diabetes mellitus (DM) is a chronic disease that affects 10% of Canadians. It classically...

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Enrichment of the Canadian Longitudinal Study on Aging with the CANJEM occupational exposure data

The CLSA offers enormous opportunities to better characterize the exposure of Canadians to harmful...

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