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CIHR Catalyst Project

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Biological dysregulation as a mechanism of unhealthy aging in older adults

Evidence suggests that a breakdown of the numerous biological systems that maintain good health...

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Relationships between risk of obstructive sleep apnea and outcomes in Parkinson’s disease in the Canadian Longitudinal Study on Aging

Obstructive sleep apnea (OSA) is a chronic condition causing obstruction of breathing passages during...

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Complexity in caregiving: characterizing non-dyadic caregiver and care-receiver relationships and their association with health-service use

Most people would prefer to stay in their own homes as they age. In...

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The health trajectory of older immigrants: inter- and intra-group analyses based on the Canadian Longitudinal Study on Aging

Aging and immigration have greatly contributed to the growing proportion of older immigrants in...

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Positive epidemiology – pre and peri-pandemic psychological resilience in older Veterans in the CLSA

How and why do some older adults adapt and thrive better than others in...

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Trajectories of work productivity loss: working from home and insights during COVID-19

People with health problems may attend at work with reduced productivity (presenteeism), take sick...

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Examining social inequalities in caregiver well-being: an analysis of CLSA data on caregiving across levels of social stratification

In Canada, a significant percentage of seniors served as caregivers, with gender differences observed...

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Cross-lagged associations between social connections and physical activity in older adults: understanding synergies and direction of effects

Physical activity (PA) and positive social connections are important for well-being, but physical inactivity...

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Using artificial intelligence to predict cardiac age and its impact on health

As we age, our functional abilities decline, but the rate of decline varies among...

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Anticholinergic and sedative medications use in the Canadian population

Some commonly used medications for depression, allergies and sleep, have been found to decrease...

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Interactive visualization of genetic variant-trait associations in the CLSA dataset

The CLSA study collected data on thousands of traits and hundreds of millions of...

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Reference values and the psychometric properties of the Life-Space Assessment in the Canadian Longitudinal Study on Aging

The Life-Space Assessment (LSA) is a questionnaire that measures everyday mobility. It assesses the...

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