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Identifying and predicting trajectories of decline in cognitive and physical function using data from Canadian Longitudinal Study of Aging (CLSA) linked to routinely collected health system data

Trajectories of cognitive decline and patterns of health care utilization and costs. There are...

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Describing, examining and predicting multimorbidity among individuals with asthma in Ontario: a population-based longitudinal study

One in three Canadians live with multimorbidity (the co-occurrence of two or more chronic...

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Fat mass to fat-free mass ratio, a new measure of sarcopenic obesity

Sarcopenic obesity is a progressive geriatric syndrome characterized by decreasing muscle mass and function...

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Understanding loneliness and allostatic load among older adults: differences by sex, social support and sleep

Loneliness has been associated with worse health among older adults. Loneliness may influence health...

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Causes and consequences of social isolation and loneliness among marginalized older adults

Social isolation and loneliness among older adults are associated with worse health, and older...

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A causal inference approach to life satisfaction and outcome-wide health

The biopsychosocial model of health emphasizes the importance of patients’ well-being in determining their...

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Hypothetical interventions for real world impact: addressing the obesity epidemic in older adults

The Canadian population is aging rapidly and older adults represent the fastest growing part...

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Broad and deep longitudinal analysis in neurodegenerative disease (BRAIN): Identifying and predicting trajectories of decline in cognitive and physical function using data from CLSA linked to routinely collected health system data (follow-up)

Declines in various aspects of cognition such as memory, language skills and reasoning are...

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The social determinants of mental and physical health during and beyond the COVID-19 pandemic

Social determinants of health (SDOH) are predictive of both chronic and acute physical and...

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Vascular risks, inflammatory activation and cognitive decline in older adults with and without depression

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Association between loneliness and medication use in Canadian adults

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Cognitive aging and dementia risk in sexual minority women

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